Topic
Triptane
About: Triptane is a research topic. Over the lifetime, 24 publications have been published within this topic receiving 127 citations. The topic is also known as: triptane.
Papers
TL;DR: Im Mittelpunkt der nicht medikamentosen Behandlung der Migrane stehen neben Empfehlungen zur Lebensfuhrung, Entspannungsverfahren (progressive Muskelrelaxation), Biofeedbackverfhren and kognitive Verhaltenstherapie.
Abstract: Die Deutsche Migrane- und Kopfschmerzgesellschaft und die Deutsche Gesellschaft fur Neurologie legen eine revidierte Fassung ihrer gemeinsamen evidenzbasierten Leitlinie fur die Therapie der Migrane vor. Zur Akuttherapie der leichten Migraneattacke wird die fruhzeitige und hochdosierte Einnahme von NSAR oder von Paracetamol empfohlen. Bei schweren Migraneattacken wird die Einnahme eines Triptans empfohlen, eine generelle Praferenz fur eine bestimmte Substanz wird hierbei nicht ausgesprochen. Zur medikamentosen Prophylaxe der Migrane werden als Substanzen der ersten Wahl Metoprolol, Propranolol, Flunarizin, Valproinsaure und Topiramat empfohlen. Substanzen der zweiten Wahl sind Amitriptylin, Venlafaxin, Gabapentin, Naproxen, Acetylsalicylsaure, Pestwurz, Magnesium und Vitamin B2. Im Mittelpunkt der nicht medikamentosen Behandlung der Migrane stehen neben Empfehlungen zur Lebensfuhrung, Entspannungsverfahren (progressive Muskelrelaxation), Biofeedbackverfahren und kognitive Verhaltenstherapie. Gerade die Kombination von nicht medikamentosen Verfahren untereinander oder mit einer medikamentosen Prophylaxe ist besonders wirksam.
53 citations
TL;DR: Methanol is converted to a mixture of hydrocarbons by reaction with zinc iodide at 200 degrees C with one highly branched alkane, 2,2,3-trimethylbutane (triptane), being obtained in surprisingly high selectivity.
Abstract: Methanol is converted to a mixture of hydrocarbons by reaction with zinc iodide at 200 °C with one highly branched alkane, 2,2,3-trimethylbutane (triptane), being obtained in surprisingly high selectivity. Mechanistic studies implicate a two-stage process, the first involving heterogeneously catalyzed formation of a carbon−carbon-bonded species, probably ethylene, that undergoes homogeneously catalyzed sequential cationic methylation to higher hydrocarbons. The first stage can be bypassed by addition of olefins, higher alcohols, or arenes, which act as initiators. Rationales for the particular activity of zinc iodide and for the selectivity to triptane are proposed.
27 citations
TL;DR: In this article, a review summarizes and analyzes the results of research in the field of triptane synthesis from methanol and dimethyl ether (DME) using both homogeneous and heterogeneous catalysts.
Abstract: The review summarizes and analyzes the results of research in the field of triptane synthesis from methanol and dimethyl ether (DME). The reaction with a fairly high triptane yield occurs in the presence of both homogeneous and heterogeneous catalysts. It has been shown that InI3 and ZnI2 are the most commonly used catalysts for the homogeneous process, while zeolite systems based on H-BEA and H-Y are promising catalysts for the heterogeneous process. The effect of the catalyst nature (acidity and structure) on the type of resulting intermediates and the reaction mechanism has been described. Currently available approaches to describing the kinetics of the complex triptane synthesis reaction and the engineering aspects of the process have been discussed.
12 citations
Patent•
2 Oct 1975TL;DR: In this article, a method for the production of triptane comprising contacting a reactant selected from methanol, dimethyl ether, or mixtures thereof, with zinc iodide at a temperature of from about 180° to about 240° C was described.
Abstract: Method for the production of triptane comprising contacting a reactant selected from methanol, dimethyl ether, or mixtures thereof, with zinc iodide at a temperature of from about 180° to about 240° C.
11 citations
Patent•
27 Feb 2002
TL;DR: In this paper, a continuous or semi-continuous process for the production of triptane and triptene from methanol and/or dimethyl ether is described, in which process co-produced water is separated from the catalyst as a vapour phase whilst the catalyst is retained in a liquid or solid phase.
Abstract: A continuous or semi-continuous process for the production of triptane and/or triptene from methanol and/or dimethyl ether in the presence in a reactor of an effective concentration of catalyst active for the conversion of methanol and/or dimethyl ether to triptane and/or triptene in which process co-produced water is separated from the catalyst as a vapour phase whilst the catalyst is retained in a liquid or solid phase. Preferably, the catalyst comprises zinc halide and is maintained in said reactor in an active form and an effective concentration. Apparatus for use in the process may comprise a reactor having at least one reaction zone and at least one separation zone.
7 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2021 | 1 |
| 2020 | 2 |
| 2019 | 3 |
| 2018 | 1 |
| 2016 | 2 |
| 2014 | 2 |