Topic
Trachelectomy
About: Trachelectomy is a research topic. Over the lifetime, 565 publications have been published within this topic receiving 12039 citations. The topic is also known as: trachelectomy.
Papers published on a yearly basis
Papers
TL;DR: In this article, the authors assess six fertility preservation techniques for young patients with cervical cancer: Dargent's procedure, simple trachelectomy or cone resection, neoadjuvant chemotherapy with conservative surgery, and laparotomic, laparoscopic and robot-assisted abdominal radical trachlectomy.
Abstract: Fertility preservation in young patients with cervical cancer is suitable only for patients with good prognostic factors and disease amenable to surgery without adjuvant therapy. Consequently, it is only offered to patients with early-stage disease (stage IB tumours 2 cm) and lymphovascular space invasion status are two main factors to determine the best fertility-sparing surgical technique. In this systematic Review, we assess six different techniques that are available to preserve fertility (Dargent's procedure, simple trachelectomy or cone resection, neoadjuvant chemotherapy with conservative surgery, and laparotomic, laparoscopic and robot-assisted abdominal radical trachelectomy). The choice between the six different fertility preservation techniques should be based on the experience of the team, discussion with the patient or couple, and, above all, objective oncological data to balance the best chance for cure with optimum fertility results for each procedure.
248 citations
TL;DR: Radical vaginal trachelectomy appears to be a valuable procedure in well-selected patients with early-stage cervical cancer, and Successful pregnancies are definitely possible after this procedure.
217 citations
TL;DR: Abdominal radical trachelectomy appears to provide equivalent oncological safety to a standard Wertheim hysterectomy using a technique familiar to all practising gynaecologic oncologists.
203 citations
TL;DR: The data demonstrate that early cervical cancer (less than 2 cm diameter) can be treated successfully with LARVT with similar efficacy and recurrence rates to LARVH, and in the experience radical trachelectomy is a safe treatment for young women affected byEarly cervical cancer who want to conserve their fertility.
193 citations
TL;DR: The data demonstrate that early cervical cancer (less than 2 cm diameter) can be treated successfully with LARVT with similar efficacy and recurrence rates to LARVH, and in the experience radical trachelectomy is a safe treatment for young women affected byEarly cervical cancer who want to conserve their fertility.
Abstract: Conventional treatment of early cervical cancer (<4 cm) is radical hysterectomy, but laparoscopic-assisted vaginal radical trachelectomy (LARVT), also known as Dargent's Operation, offers a means of radically removing the cervix, proximal parametrium, and upper vaginal cuff while preserving the body of the uterus, and thereby fertility. Retrospective studies have confirmed this procedure's oncological safety. The present study is a case-control comparison of LARVT with laparoscopic-assisted radical vaginal hysterectomy (LARVH) in women having FIGO stage I-IIA cervical cancer. LARVT was carried out in 118 patients, and LARVH in 139, in the years 1986-2003. Both procedures were accompanied by laparoscopic pelvic lymph node dissection. Women in the LARVT group were younger and fewer of them had tumors larger than 2 cm, but major prognostic factors were similar in the 2 groups. Both operations took roughly 3 hours to perform, LARVH slightly longer. Nearly half the patients underwent laparoscopic lymphadenectomy via a preperitoneal approach. Intraoperative and postoperative complications were comparably frequent in the 2 groups. Three intestinal lesions occurred in the LARVH group and 6% of women in this group were reoperated on, a majority of them because of pelvic bleeding. In the LARVT group, 11% of women were reoperated on, 9 because of bleeding. During a median follow-up of 95 months after LARVT and 113 months following LARVH, recurrences were observed in 16 women, 6% of those treated. The rate was 5.9% in the LARVT group and 3.5% in the LARVH group, not a statistically significant difference. The 5-year recurrence-free survival rate and overall survival rate approximated 95% in both surgical groups. On multivariate analysis, only tumor size and the presence or absence of lymph-vascular space invasion independently predicted recurrence; the type of operation did not. In women of reproductive age who have early cervical cancer, Dargent's operation appears to be as effective and as safe as LARVH.
190 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2025 | 7 |
| 2024 | 27 |
| 2023 | 23 |
| 2022 | 72 |
| 2021 | 49 |
| 2020 | 28 |