Topic
Thiazole
About: Thiazole is a research topic. Over the lifetime, 7949 publications have been published within this topic receiving 93294 citations. The topic is also known as: FEMA 3615 & 5H-1,3-Thiazole.
Papers published on a yearly basis
1 / 2
Papers
TL;DR: A great number of structurally diverse natural products containing five-membered heterocyclic subunits, such as imidazoles, oxazole, thiazole, and their saturated congeners, are abundant in nature and exhibit extensive and pharmacologically important biological activities.
477 citations
TL;DR: In this article, the interaction of Schiff bases with different metal ions has been studied over UV-vis absorption spectra and photofluorescent spectra, and the results indicated that Schiff base L 1 and L 2 exhibited turn-on fluorescent behavior with Al 3+ ions in methanol, which could be directly detected by the naked-eye under the UV-lamp.
Abstract: Thiazole Schiff bases 2-(4-phenyl-1,3-thiazol-2-yliminomethyl)phenol (L 1 ) and 1-(4-phenyl-1,3-thiazol-2-yliminomethyl)naphthalen-2-ol (L 2 ) have synthesized and characterized. The interaction of Schiff bases with different metal ions has been studied over UV–vis absorption spectra and photofluorescent spectra. The results are indicated that Schiff base L 1 and L 2 exhibited turn-on fluorescent behavior with Al 3+ ions in methanol, which could be directly detected by the naked-eye under the UV-lamp. The limits of detection were calculated for L 1 and L 2 since 1.0 × 10 −6 and 7.5 × 10 −7 by the titration method. Both sensors exhibited excellent fluorescent behavior in 5.0–13.5 pH range. The fluorescent behavior of legends-aluminum complex solution goes to turn-off in the presence of Ni 2+ and EDTA.
453 citations
TL;DR: In this article, the effect of deprotonation and coordination on the dimensions of parent heterocyclic thiones, especially those of pyridine-2-thione and benzo-1,3-thiazoline-2.
400 citations
TL;DR: Thiazole 3 and pyrazolo[1,5-a]pyrimidine 21 b were found to exhibit the most potent in vitro antifungal activity with MICs against A. fumigatus and F. oxysporum.
383 citations
TL;DR: The most important biological effects of thiazole-based compounds are reviewed and their roles in new leads identification and drug discovery are highlighted to help researches for finding potential future directions on the development of more potent and specific analogs of th Diazole- based compounds for various biological targets.
376 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2025 | 221 |
| 2024 | 370 |
| 2023 | 331 |
| 2022 | 488 |
| 2021 | 268 |
| 2020 | 286 |