Topic
Substrate mapping
About: Substrate mapping is a research topic. Over the lifetime, 153 publications have been published within this topic receiving 5954 citations.
Papers published on a yearly basis
Papers
Harvard University1, Loyola University Chicago2, University of Oklahoma3, University of Pennsylvania4, Pennsylvania State University5, National Heart Foundation of Australia6, Ohio State University7, University of Washington8, Henry Ford Health System9, Advocate Lutheran General Hospital10, Memorial Hospital of South Bend11, Baptist Memorial Hospital-Memphis12, University of Miami13
TL;DR: Catheter ablation is a reasonable option to reduce episodes of recurrent VT in patients with prior myocardial infarction, even when multiple and/or unmappable VTs are present, warranting surveillance and further study.
Abstract: Background— Recurrent ventricular tachycardia (VT) is an important cause of mortality and morbidity late after myocardial infarction. With frequent use of implantable cardioverter-defibrillators, these VTs are often poorly defined and not tolerated for mapping, factors previously viewed as relative contraindications to ablation. This observational multicenter study assessed the outcome of VT ablation with a saline-irrigated catheter combined with an electroanatomic mapping system. Methods and Results— Two hundred thirty-one patients (median LV ejection fraction, 0.25; heart failure in 62%) with recurrent episodes of monomorphic VT (median, 11 in the preceding 6 months) caused by prior myocardial infarction were enrolled. All inducible monomorphic VTs with a rate approximating or slower than any spontaneous VTs were targeted for ablation guided by electroanatomic mapping during sinus rhythm and/or VT. Patients were not excluded for multiple VTs (median, 3 per patient) or unmappable VT (present in 69% of pa...
760 citations
TL;DR: Elimination of LAVAs is feasible and safe and is associated with superior survival free from recurrent VT, and can be identified in most patients with scar-related VT.
Abstract: Background—Catheter ablation of ventricular tachycardia (VT) is effective and particularly useful in patients with frequent defibrillator interventions Various substrate modification techniques ha
592 citations
TL;DR: This study assesses the feasibility of guiding RF line placement by mapping to identify a reentry circuit isthmus to ablate multiple and unstable ventricular tachycardias through infarct (MI).
Abstract: Background— Extensive lines of radiofrequency (RF) lesions through infarct (MI) can ablate multiple and unstable ventricular tachycardias (VTs) Methods for guiding ablation that minimize unnecessary RF applications are needed This study assesses the feasibility of guiding RF line placement by mapping to identify a reentry circuit isthmus Methods and Results— Catheter mapping and ablation were performed in 40 patients (MI location: inferior, 28; anterior, 7; and both, 5) with an electroanatomic mapping system to measure the infarct region and ablation lines The initial line was placed in the MI region either through a circuit isthmus identified from entrainment mapping or a target identified from pace mapping A total of 143 VTs (42 stable, 101 unstable) were induced An isthmus was identified in 25 patients (63%; 5 with only stable VTs, 5 with only unstable VTs, and 15 with both VTs) Inducible VTs were abolished or modified in 100% of patients when the RF line included an isthmus compared with 53% wh
415 citations
TL;DR: In this paper, the authors aimed to prospectively assess outcomes of ventricular tachycardia (VT) ablation and identify the scar regions most prone to reentry in order to guide ablation.
Abstract: Background: Accurate and expedited identification of scar regions most prone to reentry is needed to guide ventricular tachycardia (VT) ablation. We aimed to prospectively assess outcomes of VT abl...
208 citations
TL;DR: Substrate mapping was developed to treat poorly tolerated infarct-related ventricular tachycardias (VTs) as discussed by the authors, based on 30-year-old data derived from surgical and percutaneous mapping during sinus rhythm and VT that demonstrated specific electrograms (EGMs) that characterized the arrhythmogenic substrate of VT.
207 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2021 | 11 |
| 2020 | 17 |
| 2019 | 18 |
| 2018 | 8 |
| 2017 | 2 |
| 2016 | 8 |