TL;DR: The sampling ratio (number of cores taken per unit volume of tissue) probably exceeds the sampling ratio at diagnosis, given the small volume of the gland after HIFU, and this simple classification has the most utility.
Abstract: We appreciate the interest in and comments about our recent article. We made it clear in our report that all patients were followed for ≥ 1 year from the last HIFU treatment. Patients therefore had at least three opportunities to fail biochemically. The issue of biopsy after treatment is important; there is currently no consensus on reporting standards. Previous studies on radiotherapy and cryotherapy used biopsies after treatment as an endpoint, but biopsies have largely been discontinued in favour of biochemical outcomes. Whilst the biological significance and prognostic value of these biopsies are unknown, we feel that they can give important insights in refining the conduct of novel ablation therapies such as HIFU. There are numerous changes that tend to be reported when histology is reviewed after HIFU. We summarized these changes into a binary outcome, i.e. the presence or absence of prostate cancer. Until further work is done on the significance or otherwise of other findings, we feel that this simple classification has the most utility. The sampling ratio (number of cores taken per unit volume of tissue) probably exceeds the sampling ratio at diagnosis, given the small volume of the gland after HIFU.
TL;DR: The authors analyzes the place usually assigned to Pliny the Elder in Latin literature with respect to his cultivated style and examines the meaning of stilus pressus, which the humanists assigned to sermo Plinianus at different stages of the Ciceronian controversies, because it seemed a perfect antithesis to the stilus latus of Cicero.
Abstract: This paper first analyzes the place usually assigned to Pliny the Elder in Latin literature with respect to his cultivated style. Then it examines the meaning of stilus pressus , which the humanists assigned to sermo Plinianus at different stages of the Ciceronian controversies, because it seemed a perfect antithesis to the stilus latus of Cicero.
TL;DR: Absztrakt A Biblia klasszikus korszakbeli, reneszansz kori es a kesőbbi időszakokbol szarmazo mertekado forditasai valamennyien a szokeszlet es az az allandosult szoszerkezetek előiras szerint valoforditasanak alapelvet kovetik.
Abstract: Absztrakt A Biblia klasszikus korszakbeli, reneszansz kori es a kesőbbi időszakokbol szarmazo mertekado forditasai valamennyien a szokeszlet es az allandosult szoszerkezetek előiras szerint valo forditasanak alapelvet kovetik. Nehany forditasi beszamolo azt mutatja, hogy a forditok mar a kezdetekben megegyeztek arrol, hogy a szo- es kifejezeskeszlet viszonylagos egyseget megőrzik forditasaikban. A tanulmany a szokeszlet es a jellemző bibliai stilus egysegessegenek kerdeset targyalja az Esaias profeta konyvenek aram (Targum), gorog (Septuaginta) es latin (Vulgata) forditasabol szarmazo, az isteni igazsag fogalmanak megjelolesere szolgalo kifejezeseknek az osszehasonlitasaval. A szokeszletet valojaban a bibliai stilus es az alapvető irodalmi formak jellemzői hatarozzak meg. A szerző a bibliaforditas kihivasait ennek megfelelően tagabb perspektivabol, az eszaknyugati semi nyelvek irodalmi hagyomanyainak apolasa es a bibliai stilus megőrzesenek kivanalma tavlatabol mutatja be. A szamos szinonima, antonima, al...