About: Statement (logic) is a research topic. Over the lifetime, 5488 publications have been published within this topic receiving 85291 citations. The topic is also known as: logical statement & mathematical statement.
TL;DR: The American Statistical Association (ASA) released a policy statement on p-values and statistical significance in 2015 as discussed by the authors, which was based on a discussion with the ASA Board of Trustees and concerned with reproducibility and replicability of scientific conclusions.
Abstract: Cobb’s concern was a long-worrisome circularity in the sociology of science based on the use of bright lines such as p< 0.05: “We teach it because it’s what we do; we do it because it’s what we teach.” This concern was brought to the attention of the ASA Board. The ASA Board was also stimulated by highly visible discussions over the last few years. For example, ScienceNews (Siegfried 2010) wrote: “It’s science’s dirtiest secret: The ‘scientific method’ of testing hypotheses by statistical analysis stands on a flimsy foundation.” A November 2013, article in Phys.org Science News Wire (2013) cited “numerous deep flaws” in null hypothesis significance testing. A ScienceNews article (Siegfried 2014) on February 7, 2014, said “statistical techniques for testing hypotheses...havemore flaws than Facebook’s privacy policies.” Aweek later, statistician and “Simply Statistics” blogger Jeff Leek responded. “The problem is not that people use P-values poorly,” Leek wrote, “it is that the vast majority of data analysis is not performed by people properly trained to perform data analysis” (Leek 2014). That same week, statistician and science writer Regina Nuzzo published an article in Nature entitled “Scientific Method: Statistical Errors” (Nuzzo 2014). That article is nowone of the most highly viewedNature articles, as reported by altmetric.com (http://www.altmetric.com/details/2115792#score). Of course, it was not simply a matter of responding to some articles in print. The statistical community has been deeply concerned about issues of reproducibility and replicability of scientific conclusions. Without getting into definitions and distinctions of these terms, we observe that much confusion and even doubt about the validity of science is arising. Such doubt can lead to radical choices, such as the one taken by the editors of Basic andApplied Social Psychology, who decided to ban p-values (null hypothesis significance testing) (Trafimow and Marks 2015). Misunderstanding or misuse of statistical inference is only one cause of the “reproducibility crisis” (Peng 2015), but to our community, it is an important one. When the ASA Board decided to take up the challenge of developing a policy statement on p-values and statistical significance, it did so recognizing this was not a lightly taken step. The ASA has not previously taken positions on specific matters of statistical practice. The closest the association has come to this is a statement on the use of value-added models (VAM) for educational assessment (Morganstein and Wasserstein 2014) and a statement on risk-limiting post-election audits (American Statistical Association 2010). However, these were truly policy-related statements. The VAM statement addressed a key educational policy issue, acknowledging the complexity of the issues involved, citing limitations of VAMs as effective performance models, and urging that they be developed and interpreted with the involvement of statisticians. The statement on election auditing was also in response to a major but specific policy issue (close elections in 2008), and said that statistically based election audits should become a routine part of election processes. By contrast, the Board envisioned that the ASA statement on p-values and statistical significance would shed light on an aspect of our field that is too often misunderstood and misused in the broader research community, and, in the process, provides the community a service. The intended audience would be researchers, practitioners, and science writers who are not primarily statisticians. Thus, this statementwould be quite different from anything previously attempted. The Board tasked Wasserstein with assembling a group of experts representing a wide variety of points of view. On behalf of the Board, he reached out to more than two dozen such people, all of whom said theywould be happy to be involved. Several expressed doubt about whether agreement could be reached, but those who did said, in effect, that if there was going to be a discussion, they wanted to be involved. Over the course of many months, group members discussed what format the statement should take, tried to more concretely visualize the audience for the statement, and began to find points of agreement. That turned out to be relatively easy to do, but it was just as easy to find points of intense disagreement. The time came for the group to sit down together to hash out these points, and so in October 2015, 20 members of the group met at the ASA Office in Alexandria, Virginia. The 2-day meeting was facilitated by Regina Nuzzo, and by the end of the meeting, a good set of points around which the statement could be built was developed. The next 3 months saw multiple drafts of the statement, reviewed by group members, by Board members (in a lengthy discussion at the November 2015 ASA Board meeting), and by members of the target audience. Finally, on January 29, 2016, the Executive Committee of the ASA approved the statement. The statement development process was lengthier and more controversial than anticipated. For example, there was considerable discussion about how best to address the issue of multiple potential comparisons (Gelman and Loken 2014). We debated at some length the issues behind the words “a p-value near 0.05 taken by itself offers only weak evidence against the null
TL;DR: The systematic development and scope of SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2013 is described, a guideline for the minimum content of a clinical trial protocol.
Abstract: The protocol of a clinical trial serves as the foundation for study planning, conduct, reporting, and appraisal. However, trial protocols and existing protocol guidelines vary greatly in content and quality. This article describes the systematic development and scope of SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2013, a guideline for the minimum content of a clinical trial protocol.The 33-item SPIRIT checklist applies to protocols for all clinical trials and focuses on content rather than format. The checklist recommends a full description of what is planned; it does not prescribe how to design or conduct a trial. By providing guidance for key content, the SPIRIT recommendations aim to facilitate the drafting of high-quality protocols. Adherence to SPIRIT would also enhance the transparency and completeness of trial protocols for the benefit of investigators, trial participants, patients, sponsors, funders, research ethics committees or institutional review boards, peer reviewers, journals, trial registries, policymakers, regulators, and other key stakeholders.
TL;DR: The Tractatus Logico-Philosophicus as mentioned in this paper is a remarkable and strikingly original work which is published in German and English in parallel pages and it is difficult to appreciate the reason for this, seeing that the author is evidently familiar with our language and has himself carefully revised the proofs of the translation.
Abstract: 13 EADERS of Mr. Bertrand Russell's philosophical £v works know that one of his pupils before the outbreak of the war, an Austrian, Mr. Ludwig Wittgenstein, caused him to change his views in some important particulars. Curiosity can now be satisfied. The “Tractatus Logico-Philosophicus “which Mr. Ogden has included in his new library of philosophy is a remarkable and strikingly original work. It is published in German and English in parallel pages. It is difficult to appreciate the reason for this, seeing that the author is evidently familiar with our language and has himself carefully revised the proofs of the translation. Also we should have liked to have the Tractatus without Mr. Russell's Introduction, not, we hasten to add, on account of any fault or shortcoming in that introduction, which is highly appreciative and in part a defence of himself, in part explanatory of the author, but for the reason that good wine needs no bush and that Mr. Russell's bush has the unfortunate effect of dulling the palate instead of whetting the appetite. In his penultimate sentence Mr. Russell says; “To have constructed a theory of logic which is not at any point obviously wrong is to have achieved a work of extraordinary difficulty and importance.” We agree, but how uninspiring when compared with Mr. Wittgenstein's own statement of aim: “What can be said at all can be said clearly, and whereof one cannot speak, thereof one must be silent.” Tractatus Logico-Philosophicus. By Ludwig Wittgenstein. (International Library of Psychology, Philosophy and Scientific Method.) Pp. 189. (London: Kegan Paul and Co., Ltd.; New York: Harcourt, Brace and Co., Inc., 1922.) 10s. 6d. net.
TL;DR: In this article, the authors show how to convert the raw results of any statistical procedure into expressions that convey numerically precise estimates of the quantities of greatest substantive interest, include reasonable measures of uncertainty about those estimates, and require little specialized knowledge to understand.
Abstract: W e show that social scientists often do not take full advantage of the information available in their statistical results and thus miss opportunities to present quantities that could shed the greatest light on their research questions. In this article we suggest an approach, built on the technique of statistical simulation, to extract the currently overlooked information and present it in a reader-friendly manner. More specifically, we show how to convert the raw results of any statistical procedure into expressions that (1) convey numerically precise estimates of the quantities of greatest substantive interest, (2) include reasonable measures of uncertainty about those estimates, and (3) require little specialized knowledge to understand. The following simple statement satisfies our criteria: “Other things being equal, an additional year of education would increase your annual income by $1,500 on average, plus or minus about $500.” Any smart high school student would understand that sentence, no matter how sophisticated the statistical model and powerful the computers used to produce it. The sentence is substantively informative because it conveys a key quantity of interest in terms the reader wants to know. At the same time, the sentence indicates how uncertain the researcher is about the estimated quantity of interest. Inferences are never certain, so any honest presentation of statistical results must include some qualifier, such as “plus or minus $500” in the present example. Making the Most of Statistical Analyses: Improving Interpretation and Presentation
Alessandro Liberati, Douglas G. Altman, Jennifer Tetzlaff, Cynthia D. Mulrow, Peter C Gøtzsche, John P. A. Ioannidis, Mike Clarke, P.J. Devereaux, Jos Kleijnen, David Moher
TL;DR: The PRISMA statement is a reporting guideline for systematic reviews and meta-analyses of health care interventions that aims to improve the clarity and transparency of these reports.
Abstract: Systematic reviews and meta-analyses are essential to summarize evidence relating to efficacy and safetyof health care interventions accurately and reliably. The clarity and transparency of these reports, however,is not optimal. Poor reporting of systematic reviews diminishes their value to clinicians, policy makers, andother users. Since the development of the QUOROM (QUality Of Reporting Of Meta-analysis) Statement—areporting guideline published in 1999—there have been several conceptual, methodological, and practicaladvances regarding the conduct and reporting of systematic reviews and meta-analyses. Also, reviews ofpublished systematic reviews have found that key information about these studies is often poorly reported.Realizing these issues, an international group that included experienced authors and methodologistsdeveloped PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) as an evolution ofthe original QUOROM guideline for systematic reviews and meta-analyses of evaluations of health careinterventions. The PRISMA Statement consists of a 27-item checklist and a four-phase flow diagram. Thechecklist includes items deemed essential for transparent reporting of a systematic review. In thisExplanation and Elaboration document, we explain the meaning and rationale for each checklist item. Foreach item, we include an example of good reporting and, where possible, references to relevant empiricalstudies and methodological literature. The PRISMA Statement, this document, and the associated Web site(http://www. prisma-statement.org/) should be helpful resources to improve reporting of systematicreviews and meta-analyses.