Topic
Splenial
About: Splenial is a research topic. Over the lifetime, 245 publications have been published within this topic receiving 2500 citations.
Papers published on a yearly basis
Papers
Journal Article•
TL;DR: The clinical features among the affected patients were nearly identical, consisting of relatively mild CNS manifestations and complete recovery within 1 month of neurologic symptoms.
Abstract: Objective: To clarify whether patients with clinical diagnoses of encephalitis/encephalopathy with a reversible lesion in the splenium of the corpus callosum (SCC) share common clinical features. Methods: Possible encephalitis/encephalopathy patients with a reversible isolated SCC lesion on MRI were collected retrospectively. Their clinical, laboratory, and radiologic data were reviewed. Results: Fifteen encephalitis/encephalopathy patients with a reversible isolated SCC lesion were identified among 22 patients referred for this study. All 15 patients had relatively mild clinical courses. Twelve of the 15 patients had disorders of consciousness. Eight patients had seizures, and three of them received antiepileptic drugs. All 15 patients clinically recovered completely within 1 month (8 patients within a week) after the onset of neurologic symptoms. The SCC lesion was ovoid in six patients; it extended irregularly from the center to the lateral portion of SCC in the other eight patients. Homogeneously reduced diffusion was seen in all seven patients who underwent diffusion-weighted imaging. There was no enhancement in the five patients so examined. The SCC lesion had completely disappeared in all patients at follow-up MRI exams between 3 days and 2 months after the initial MRI (within 1 week in eight patients). Conclusion: The clinical features among the affected patients were nearly identical, consisting of relatively mild CNS manifestations and complete recovery within 1 month.
158 citations
Journal Article•
TL;DR: Four patients with encephalitis/encephalopathy and parenchymal lesions accompanying reversible splenial lesions were retrospectively evaluated and previous observations suggest a less severe course and outcome for patients with reversible lesions isolated to thesplenium or to the splenium and peripheral frontoparietal white matter.
Abstract: Four patients with encephalitis/encephalopathy and parenchymal lesions accompanying reversible splenial lesions were retrospectively evaluated. In 3 patients, reversible lesions with transiently reduced diffusion were seen in the splenium and symmetrically in the peripheral frontoparietal white matter, clinical signs and symptoms were mild, and recovery was complete. These and previous observations suggest a less severe course and outcome for patients with reversible lesions isolated to the splenium or to the splenium and peripheral frontoparietal white matter.
150 citations
1 Jan 2006
TL;DR: A transient lesion of the SCC is a significant but nonspecific finding and may be the only detectable change in patients with good prognosis, indicating a clinically mild form of encephalitis/encephalopathy.
Abstract: Three patients, who had drowsiness and new-onset convulsions, recovered spontaneouslywithout any medication. In the other 2 seizure-free patients, 1 had trigeminal neuralgia and headacheand the other had facial numbness and left upper monoparesis. All patients had round well-definedovoid hyperintense splenial lesions (14.94 1.87 mm) on DWI with a significantly low apparentdiffusion coefficient (ADC) of 0.41 0.05 10
121 citations
TL;DR: In this paper, the authors illustrate acquired diseases or conditions of the corpus callosum that may be found by magnetic resonance (MR) imaging of the brain, including infarction, bleeding, diffuse axonal injury, multiple sclerosis, acute disseminated encephalomyelitis, Marchiafava-Bignami disease, glioblastoma, gliomatosis cerebri, lymphoma, metastasis, germinoma, infections, metabolic diseases, transient splenial lesion, dilated Virchow-Robin spaces, wallerian degeneration
Abstract: In this pictorial review, we illustrate acquired diseases or conditions of the corpus callosum that may be found by magnetic resonance (MR) imaging of the brain, including infarction, bleeding, diffuse axonal injury, multiple sclerosis, acute disseminated encephalomyelitis, Marchiafava-Bignami disease, glioblastoma, gliomatosis cerebri, lymphoma, metastasis, germinoma, infections, metabolic diseases, transient splenial lesion, dilated Virchow-Robin spaces, wallerian degeneration after hemispheric damage and focal splenial gliosis. MR imaging is useful for the detection and differential diagnosis of corpus callosal lesions. Due to the anatomical shape and location of the corpus callosum, both coronal and sagittal fluid-attenuated inversion recovery images are most useful for visualizing lesions of this structure.
97 citations
TL;DR: There is good evidence for transfer of word information and a remarkable degree of functional specificity within the corpus callosum, which suggests that the spared splenial fibres in VP's corpusCallosum are material-specific.
Abstract: Patient VP underwent complete callosotomy for the control of intractable epilepsy at the age of 27 years. Subsequent MRI, however, revealed spared callosal fibres in the rostral and splenial ends of the corpus callosum. We report a series of experiments designed to determine whether these fibres support functional transfer of information between the two cerebral hemispheres. Although we found no evidence for transfer of colour, shape or size information, there is good evidence for transfer of word information. This suggests that the spared splenial fibres in VP's corpus callosum are material-specific. The results of these experiments illustrate the remarkable degree of functional specificity within the corpus callosum
89 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2022 | 1 |
| 2021 | 26 |
| 2020 | 23 |
| 2019 | 14 |
| 2018 | 22 |
| 2017 | 19 |