Topic
Solketal
About: Solketal is a research topic. Over the lifetime, 328 publications have been published within this topic receiving 7484 citations.
Papers published on a yearly basis
Papers
TL;DR: This paper provides a comprehensive review and critical analysis on the different reaction pathways for catalytic conversion of glycerol into commodity chemicals, including selective oxidation, selective hydrogenolysis, selective dehydration, pyrolysis and gasification, steam reforming, thermal reduction into syngas, selective transesterification, selective etherification, oligomerization and polymerization, and conversion of Glycerol carbonate.
Abstract: New opportunities for the conversion of glycerol into value-added chemicals have emerged in recent years as a result of glycerol's unique structure, properties, bioavailability, and renewability. Glycerol is currently produced in large amounts during the transesterification of fatty acids into biodiesel and as such represents a useful by-product. This paper provides a comprehensive review and critical analysis on the different reaction pathways for catalytic conversion of glycerol into commodity chemicals, including selective oxidation, selective hydrogenolysis, selective dehydration, pyrolysis and gasification, steam reforming, thermal reduction into syngas, selective transesterification, selective etherification, oligomerization and polymerization, and conversion of glycerol into glycerol carbonate.
1,645 citations
TL;DR: In this paper, the acid-catalysed condensation of glycerol, a chemical from renewable materials, with benzaldehyde, formaldehyde, acetone, and their dimethyl acetals to mixtures of [1,3]dioxan-5-ols and [ 1,3]-dioxolan-4-yl-methanols was investigated.
327 citations
TL;DR: The potential bioavailability improvement of mycophenolic acid (MPA) through ester derivatization was evaluated in monkeys at a dose of 20 mg/kg in this study and the better bioavailability of ester 4 may result from its greater partitioning into the gastrointestinal membranes.
Abstract: The potential bioavailability improvement of mycophenolic acid (MPA), 1, through ester derivatization was evaluated in monkeys at a dose of 20 mg/kg in this study. The acetyl solketal ester 3 was found to have excellent partition properties but poor aqueous solubility. Thus, even though it can be converted rapidly to MPA by plasma and liver enzymes, it showed poor oral bioavailability (56% of MPA) in monkeys. The bioavailability of the morpholinoethyl ester 4 and the acetyl morpholinoethyl ester 5, on the other hand, was found to be 236 and 150% that of MPA, respectively. Since ester 5 has greater aqueous solubility, but similar chemical stability and enzymatic hydrolysis rates compared to ester 4, the better bioavailability of ester 4 may result from its greater partitioning into the gastrointestinal membranes.
265 citations
TL;DR: In this paper, a mixture of glycerin and formaldehyde was used to produce the correspondent ketal (solketal) and acetal, respectively, which were blended in 1, 3, and 5 vol % with gasoline containing 0 and 25 vol % ethanol.
Abstract: Glycerin was reacted with acetone and formaldehyde to produce the correspondent ketal (solketal) and acetal, respectively. These compounds were blended in 1, 3, and 5 vol % with gasoline containing 0 and 25 vol % ethanol. The addition of the glycerin derivatives did not significantly change the distillation curve of the gasolines. The solketal reduced the gum formation in both gasolines (with and without ethanol) and increased the octane number up to 2.5 points in the gasoline without ethanol. The glycerin/formaldehyde acetal was only soluble in the gasoline containing ethanol and led to an increase in gum formation and a slight reduction (up to −0.75 points) in the octane number. These results indicate that solketal has a potential for blending with regular gasoline and may be an alternative for the glycerin produced from biodiesel.
258 citations
TL;DR: In this article, the acid-catalysed reaction of glycerol with aqueous formaldehyde and acetone in absence of solvents and using heterogeneous catalysts was studied.
247 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2022 | 3 |
| 2021 | 35 |
| 2020 | 38 |
| 2019 | 38 |
| 2018 | 27 |
| 2017 | 34 |