About: Ross procedure is a research topic. Over the lifetime, 1001 publications have been published within this topic receiving 17614 citations. The topic is also known as: pulmonary autograft.
TL;DR: The finding of late degenerative changes in a proportion of aortic homografts prompted the use of the patient's own pulmonary valve as a replacement, and as a living autograft, the transplanted pulmonary valve has the prospect of long-term or permanent survival, whilst retaining the advantages of an aortiograft.
TL;DR: Patients with bic Suspid aortic valve disease have more severe degenerative changes in the media of the ascending aorta and main pulmonary artery than patients with tricuspid aortsid valve disease.
TL;DR: The findings support the hypothesis that a living valve implanted in the aortic position can significantly improve the long-term outcomes in patients.
TL;DR: Dilation of the pulmonary autograft after the Ross procedure may occur because of an intrinsic abnormality of themonary root in patients with congenital aortic valve disease.
TL;DR: Although the pulmonary-autograft procedure is more complex than simple aortic-valve replacement, it has been safely applied in selected patients, including young adults and may be the best available substitute for diseased aortIC valves in children and young adults.
Abstract: Background The optimal substitute for severely diseased aortic valves in children and young adults is unknown. The use of a mechanical prosthesis requires permanent treatment of the patient with anticoagulants and is associated with thromboembolic and hemorrhagic complications. Aortic-valve allografts and porcine bioprostheses, which do not necessitate anticoagulant therapy, may deteriorate and have limited durability. Methods We therefore evaluated the use of the autologous pulmonary valve (i.e., the patient's own pulmonary valve) and the adjacent pulmonary artery as a replacement for the aortic valve and aortic sinuses in 33 patients. Five of the patients were from 8 to 16 years of age, and 28 were from 20 to 47 years of age. The pulmonary valve and the main pulmonary artery were used to replace the diseased aortic valve and the adjacent aorta. The coronary arteries were detached from the aorta and implanted into the pulmonary artery. The pulmonary valve and artery were replaced with a cryopreserved pul...