Topic
Rome process
About: Rome process is a research topic. Over the lifetime, 10 publications have been published within this topic receiving 1300 citations.
Papers
TL;DR: In child/adolescent Rome IV the era of diagnosing a FGID only when organic disease has been excluded is waning, as evidence to support symptom-based diagnosis is waning and the dictum that there was no evidence for organic disease in all definitions is removed.
1,088 citations
TL;DR: The criteria developed through the Rome process, currently in its third iteration, have been those most widely employed in clinical trials and, therefore, most relevant to any review of the literature on the management of these disorders.
660 citations
TL;DR: The Rome process has had a major impact, and Rome criteria are now used for the entry into most clinical trials, so that classifications must of necessity be symptom based.
Abstract: Rome II: the Functional Gastrointestinal Disorders. Diagnosis, Pathophysiology and Treatment: a Multinational Consensus . 2nd edn. Edited by Drossman DA, Corazziari E, Talley J, et al . (Pp 800; illustrated; $79.95) USA: Degnon Associates, 2000. ISBN 0965683729 (PB).
While medical students can confidently hold forth on the mechanisms of the Zollinger-Ellison syndrome, a condition affecting one in a million of the population, they rarely have much to say about functional GI disorders (FGIDs), which can affect up to a quarter of the population at some stage in their life. Part of the reason is that this is a complex area, which requires the integration of pathophysiology with psychology, and even sociology. FGIDs also suffer from having no objective measurable abnormalities, so that classifications must of necessity be symptom based. The Rome process is a valiant attempt to make this area of study less confused, more consistent, and scientifically respectable. As such, it undoubtedly has had a major impact, and Rome criteria are now used for the entry into most clinical trials …
303 citations
TL;DR: The main changes include the use of epidemiology‐based symptom thresholds to define FGIDs, characterization of FGIDS as disorders of Gut‐Brain interaction, and updates of criteria for esophageal disorders, irritable bowel syndrome and Biliary and Sphincter of Oddi disorders based on scientific and technical progress made over the last decade.
Abstract: The functional gastrointestinal disorders (FGIDs) are the most common disorders seen in Gastroenterology clinical practice. The Rome process has generated consensus definitions of FGIDS, allowing to subdivide patients into diagnostic categories based on the symptom pattern. The Rome IV consensus, presented in 2016, is the most recent update of this diagnostic scheme. This article summarizes the main changes, which include the use of epidemiology-based symptom thresholds to define FGIDs, characterization of FGIDS as disorders of Gut-Brain interaction, and updates of criteria for esophageal disorders, irritable bowel syndrome and Biliary and Sphincter of Oddi disorders based on scientific and technical progress made over the last decade. The Rome IV consensus provides a standard for clinical and research approach to FGIDS for the coming years.
76 citations
TL;DR: While the staple approaches of acid suppression and eradication of Helicobacter pylori have some limited efficacy in select populations, strategies to ameliorate symptoms in the majority of sufferers based on presumed pathophysiology have largely foundered.
52 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2019 | 1 |
| 2017 | 2 |
| 2016 | 2 |
| 2014 | 1 |
| 2013 | 2 |
| 2007 | 1 |