TL;DR: MR imaging is more sensitive than CT in detecting neoplastic invasion of cartilage, but the inability to differentiate between nonneoplastic inflammatory changes and tumor with MR imaging leads to overestimation of neoplastics invasion.
Abstract: PURPOSE: To compare the usefulness of computed tomography (CT) and gadolinium-enhanced magnetic resonance (MR) imaging in the detection of neoplastic invasion of laryngeal cartilage. MATERIALS AND METHODS: In a prospective study, 53 patients with carcinoma of the larynx or piriform sinus underwent CT and MR imaging before total or partial laryngectomy. The findings at imaging and pathologic examination were compared. RESULTS: At histologic examination, neoplastic invasion of cartilage was present in 34 patients and absent in 19. MR imaging was more sensitive than CT (89% vs 66%; P = .001). Inflammatory changes and fibrosis, however, were indistinguishable from tumor on MR images, resulting in overestimation of neoplastic invasion in a large number of patients. Therefore, MR imaging was less specific than CT (84% vs 94%; P = .004). CONCLUSION: MR imaging is more sensitive than CT in detecting neoplastic invasion of cartilage, but the inability to differentiate between nonneoplastic inflammatory changes and...
TL;DR: A comparatively low local recurrence rate, a high recurrence-free survival rate, and the avoidance of laryngectomy favor function-preserving surgery of piriform sinus carcinomas.
Abstract: OBJECTIVE: To determine the effectiveness of organ-preserving CO2 laser microsurgery for the treatment of piriform sinus carcinoma.METHODS: A retrospective review of 129 previously untreated patien...
TL;DR: CT measurement of the piriform aperture width is a simple and accurate method for diagnosing CNPAS; a width less than 11 mm in a term infant is considered to be diagnostic.
Abstract: PURPOSE: To describe the computed tomographic (CT) measurements and features that enable accurate diagnosis of congenital nasal piriform aperture stenosis (CNPAS). MATERIALS AND METHODS: The clinical and imaging features of six patients (age range, 0–11 months) with CNPAS were retrospectively evaluated and compared with those of 61 control subjects younger than 24 months. RESULTS: The average widths of the piriform aperture in patients aged 0–3, 4–6, and 10–12 months were 4.8, 7.0, and 6.0 mm, respectively, compared with 13.4 (P < .001), 14.9, and 15.6 mm, respectively, in the age-matched control subjects. The average areas of the piriform aperture in patients in the three age groups measured 0.24, 0.46, and 0.36 cm2, respectively, compared with 0.67 (P < .001), 0.86, and 1.11 cm2, respectively, in the age-matched control subjects. The width of the nasal cavity in patients with CNPAS was in the less than 5th percentile compared with that in the control subjects. Abnormal dentition and a midline bone ridge...
TL;DR: To assess the feasibility of transoral laser microsurgery in the treatment of hypopharyngeal cancer, with a special focus on piriform sinus carcinomas, and to report the oncologic and functional outcomes.
Abstract: Objective:To assess the feasibility of transoral laser microsurgery (TLM) in the treatment of hypopharyngeal cancer, with a special focus on piriform sinus carcinomas, and to report the oncologic and functional outcomes.Study Design:Prospective case-series study at a single institute, an academic te
TL;DR: It is concluded that the piriform sinus fistula is the most common underlying abnormality in patients with AST and recurrence of inflammation can be prevented by complete fistulectomy.
Abstract: We have previously reported that an internal fistula (piriform sinus fistula) was the apparent route of infection in 15 patients with acute suppurative thyroiditis (AST). Here, we describe 43 patients with AST, most of whom had a demonstrable fistula.
The characteristic clinical features included: onset in infancy or childhood in 74% of cases, a left-sided predominance of involvement (40∶3), and frequent recurrence. Twenty-nine patients had had several previous episodes of AST. The fistula was demonstrable in 38 of 42 patients examined by barium meal. Twenty-seven patients underwent fistulectomy. Six of 16 patients who declined fistulectomy had recurrences and 2 of them underwent surgery thereafter. None of 29 patients who had fistulectomy developed recurrences, except for 2 patients in whom the fistula could not be removed completely. The fistula ended medial or lateral to the thyroid lobe, attached to or entered the lobe in 6, 3, 6, and 12 cases, respectively. The thyroid specimens showed several features of inflammatory change.
Thus, we concluded that the piriform sinus fistula is the most common underlying abnormality in patients with AST. Recurrence of inflammation can be prevented by complete fistulectomy.