TL;DR: It was concluded that eyelid malignancies (BCC and SCC), photokeratitis, CDK, pterygium, and cortical cataract are strongly associated with UVR exposure.
Abstract: The objective of this study is to review the association between ultraviolet (UV) light and ocular diseases. The data are sourced from the literature search of Medline up to Nov 2012, and the extracted data from original articles, review papers, and book chapters were reviewed. There is a strong evidence that ultraviolet radiation (UVR) exposure is associated with the formation of eyelid malignancies [basal cell carcinoma (BCC) and squamous cell carcinoma (SCC)], photokeratitis, climatic droplet keratopathy (CDK), pterygium, and cortical cataract. However, the evidence of the association between UV exposure and development of pinguecula, nuclear and posterior subcapsular cataract, ocular surface squamous neoplasia (OSSN), and ocular melanoma remained limited. There is insufficient evidence to determine whether age-related macular degeneration (AMD) is related to UV exposure. It is now suggested that AMD is probably related to visible radiation especially blue light, rather than UV exposure. From the results, it was concluded that eyelid malignancies (BCC and SCC), photokeratitis, CDK, pterygium, and cortical cataract are strongly associated with UVR exposure. Evidence of the association between UV exposure and development of pinguecula, nuclear and posterior subcapsular cataract, OSSN, and ocular melanoma remained limited. There is insufficient evidence to determine whether AMD is related to UV exposure. Simple behaviural changes, appropriate clothing, wearing hats, and UV blocking spectacles, sunglasses or contact lens are effective measures for UV protection.
TL;DR: It is found that a commercially available HR-OCT was a useful noninvasive adjunctive tool in the diagnosis of ocular surface lesions and differentiating among various lesions based on optical signs.
Abstract: Purpose To evaluate the use of a commercially available, high-resolution, spectral-domain optical coherence tomography (HR-OCT) device in the diagnosis of corneal and conjunctival pathologies, with a focus on malignant lesions. Methods Eighty-two eyes of 71 patients were enrolled in this prospective case series, including 10 normal eyes, 21 with ocular surface squamous neoplasia (OSSN), 24 with a pterygium or pingueculum, 3 with lymphoma, 18 with pigmented conjunctival lesions (nevus, flat melanosis, or melanoma), and 6 with Salzmann nodular degeneration. Subjects were imaged using photography and HR-OCT (RTVue, Optovue, Fremont, CA). When clinically indicated, surgery was performed and histopathologic specimens were correlated with OCT images. Results HR-OCT was useful in differentiating among various lesions based on optical signs. Specifically, in OSSN, HR-OCT findings included epithelial thickening and hyper-reflectivity, whereas pterygia and pinguecula showed a subepithelial mass under thinner epithelium. In lymphoma, a hypo-reflective, homogenous subepithelial mass was observed. Differentiating between pigmented lesions with HR-OCT was more difficult, but certain characteristics could be identified. Eyes with nevi and melanoma both displayed intensely hyper-reflective basal epithelial layers and discrete subepithelial lesions, but could be differentiated by the presence of cysts in nevi and intense shadowing of sublesional tissue in most melanomas. Conclusion We found that a commercially available HR-OCT was a useful noninvasive adjunctive tool in the diagnosis of ocular surface lesions.
TL;DR: In 17 patients with corneal intraepithelial neoplasia (dysplasia), the epithelium formed a gray plaque at the cornea adjacent to a conjunctival papilloma in seven cases, leukoplakia in six cases, a pterygium in one cases, and a pinguecula in one case.
TL;DR: This study concerns the status of pterygium and pinguecula according to age and gender in the population of Tehran, which suggests lower prevalence rates in Tehran.
Abstract: To determine the prevalence and causes of pterygium and pinguecula in the population of Tehran in 2002. In a cross-sectional population study with cluster sampling, 6497 residents of Tehran were selected from 160 clusters. Samples were chosen according to a door-to-door head counting and were then invited for free examinations. After the interview, ophthalmic examinations were performed at an eye clinic. Of the selected sample, 4564 people (70.3%) participated in the study. The age- and gender-standardized prevalence of pterygium in this population was 1.3% (95% confidence interval (CI): 0.9–1.6%). The prevalence of pterygium was 1.4 and 1.1% in men and women, respectively (P>0.05). The prevalence of pinguecula in this study was 22.5% (95% CI: 21.1–24.0%); 27.1% in men and 17.7% in women (P<0.001). In both genders, the prevalence of pterygium and pinguecula showed a significant increase with age (P<0.001). This study concerns the status of pterygium and pinguecula according to age and gender in the population of Tehran. The overall prevalence rates were 1.3 and 22.5% for pterygium and pinguecula, respectively. The comparison of the results with those reported from other areas of the world suggests lower prevalence rates in Tehran.