Topic
Piliostigma
About: Piliostigma is a research topic. Over the lifetime, 19 publications have been published within this topic receiving 496 citations.
Papers
TL;DR: It is suggested that the inhibitory properties of some of these Nigerian plant extracts against GST may contribute to the pharmacological basis of their efficacy against helminths in traditional herbal use.
Abstract: Piliostigma thonningii, Ocimum gratissimum, Nauclea latifolia and Alstonia boonei are used in Nigerian traditional medicines against gastrointestinal helminths of animals and man. Proanthocyanidins were detected in Piliostigma and Nauclea, but not Alstonia or Ocimum. Extracts of these plants killed 50% of brine shrimp nauplii at <10 ppm (Nauclea), 100 ppm (Piliostigma) and <1000 ppm (Ocimum and Alstonia), the Nauclea LD50 being similar to the anthelmintic drug piperazine. Extracts were also toxic to the parasitic nematode Haemonchus infective L3 stage. Nematode glutathione-S-transferases (GSTs) are potential drug targets. Apart from Alstonia all the medicinal plants contained heat-stable inhibitory activities against recombinant Ascaris and Onchocerca GSTs in vitro. Piliostigma, Ocimum and Nauclea had IC50s of 2, 10 and 15 microg/mL respectively for Ascaris GST and 4, 8, 28 microg/mL respectively for Onchocerca GST. We suggest that the inhibitory properties of some of these Nigerian plant extracts against GST may contribute to the pharmacological basis of their efficacy against helminths in traditional herbal use.
93 citations
1 Jan 2010
TL;DR: The tribe Cercideae is reorganized into 12 genera plac ed in two subtribes, Cercidinae (A denolobus , Cercis , Griffonia ) and Bauhiniinae and a key to the subtribes and genera is provided.
Abstract: The tribe Cercideae is reorganized into 12 genera plac ed in two subtribes, Cercidinae (A denolobus , Cercis , Griffonia ) and Bauhiniinae ( Bauhinia , Barklya , Brenierea , Gigasiphon , Lysiphyllum , Phanera , Piliostigma , Schnella , Tylosema ). A key to the subtribes and genera is provided.
74 citations
Journal Article•
TL;DR: Piliostigma thionningii (Schumach Milne-Redhead leaves from Idu Area of the Federal Capital Territory (FCT) Abuja, Nigeria, were collected and qualitatively analyzed for identification of phytochemical constituents as discussed by the authors.
Abstract: Piliostigma thionningii (Schumach) Milne-Redhead leaves from Idu Area of the Federal Capital Territory (FCT) Abuja. Nigeria, were collected and qualitatively analyzed for identification of phytochemical constituents. The results showed the presence of bioactive constituents of carbohydrates, glycosides, flavonoids, tannins, saponins, balsams, volatile oil, and terpenes. Phlobatannins, resins, alkaloids, anthraquinones and sterols were not detected. The proximate analysis of the leaves revealed a composition of 9.90% moisture content, 4.62% total ash value, 11.28% alcohol soluble extractive value, 2.50% water soluble extractive value and 0.91% acid insoluble ash value. More research work is recommended on the plant leaves for isolation and characterization of bioactive compounds that may be active against malaria parasites and other diseases.
36 citations
31 citations
TL;DR: In this paper, the cellulosic fibers extracted from the bark of Piliostigma racemosa plant were used to assess the suitability of these fibers for reinforcing po...
Abstract: The purpose of this present investigation is to characterize the cellulosic fibers extracted from the bark of Piliostigma racemosa plant to assess the suitability of these fibers for reinforcing po...
27 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2021 | 1 |
| 2018 | 1 |
| 2016 | 2 |
| 2015 | 1 |
| 2013 | 4 |
| 2011 | 1 |