About: Pheneticillin is a research topic. Over the lifetime, 2 publications have been published within this topic receiving 62 citations. The topic is also known as: (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenoxypropanoyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid & Pheneticillin.
TL;DR: No significant difference was found between prophylactic single doses of phenethicillin and clindamycin with regard to postoperative infection in patients undergoing local bone augmentation procedures.
TL;DR: This penicillin EIA showed broad group‐specificity for penicillins having the intact 6‐aminopenicillanic acid (6‐APA) nucleus, and was able to detect 16 other penicilledins tested, whereas cephalosporin antibiotics were not detected.
Abstract: Polyclonal antibodies against penicillin antibiotics were produced in rabbits after immunization with an ampicillin‐bovine serum albumin conjugate. The antibodies were tested in a competitive direct enzyme immunoassay (EIA) using an ampicillin‐horseradish peroxidase conjugate as the labelled antigen and penicillin G as the reference antibiotic. The 50% inhibition concentration for penicillin G was 12 ng ml−1. This penicillin EIA showed broad group‐specificity for penicillins having the intact 6‐aminopenicillanic acid (6‐APA) nucleus, and was able to detect 16 other penicillins tested, whereas cephalosporin antibiotics were not detected. Relative cross‐reactivities (penicillin G = 100%) exceeding 10% were found for amoxicillin (45%), ampicillin (45%), 6–8 (12%), azlocillin (110%), carbenicillin (39%), cloxacillin (49%), dicloxacillin (57%), epicillin (23%), metampicillin (130%), methicillin (32%), oxacillin (98%), penicillin V (160%), pheneticillin (68%), piperacillin (26%) and ticarcillin (110%). After al...