Topic
Phenacyl bromide
About: Phenacyl bromide is a research topic. Over the lifetime, 585 publications have been published within this topic receiving 5725 citations. The topic is also known as: omega-Bromoacetophenone & alpha-Bromoacetophenone.
Papers published on a yearly basis
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Papers
TL;DR: The visible-light-promoted photocatalytic activity of a highly porous carbazolic organic framework, Cz-POF-1, toward three prototypic organic transformations was reported in this article.
Abstract: We report the visible-light-promoted photocatalytic activity of a highly porous carbazolic organic framework, Cz-POF-1, toward three prototypic organic transformations: net reductive dehalogenation of phenacyl bromide and its derivatives, net oxidative hydroxylation of arylboronic acids, and redox-neutral α-alkylation of aldehydes. We show that the extended π-conjugation in Cz-POF-1 enhances its visible light absorption, and the large porosity accelerates the reaction rate. For α-alkylation of aldehydes, Cz-POF-1 requires less strict reaction conditions and can be easily recovered and reused for up to 10 times. This work reveals a bright future for Cz-POFs as a new generation of metal-free photocatalysts for organic synthesis.
242 citations
TL;DR: In this paper, a predesigned imine-based COF with electron donor and acceptor structure was proposed for reductive dehalogenation of phenacyl bromide derivatives and α-alkylation of aldehydes.
Abstract: Visible-light active, heterogeneous, and organic photocatalysts exhibit a more sustainable and environmentally friendly alternative to classical metal-based catalysts. Two-dimensional covalent organic frameworks (2D-COFs) with permanent porosity, columnar π-arrays and excellent stability, that can become an excellent platform for heterogeneous photocatalysis of organic transformations. Here we report a predesigned imine-based COF with electron donor and acceptor structure. And new framework possesses large surface area, high crystallinity, outstanding stability and broad absorption range in the visible-light region as well as good photoelectric response characteristics. Importantly, it was found to be a highly effective heterogeneous photocatalyst for reductive dehalogenation of phenacyl bromide derivatives and α-alkylation of aldehydes under irradiation of visible-light. In addition, the COF gave good recyclability and could be reused after a simple separation manipulation. The current present still reveals a great prospect for 2D-COFs as metal-free, heterogeneous photocatalysts for organic transformations.
222 citations
TL;DR: Preliminary results reveal that some of the synthesized compounds are showing promising antimicrobial activity, and were screened for their antibacterial and antifungal activities.
219 citations
TL;DR: 5-bromo-6-(4-chlorophenyl)-2-cyclopropylimidazo[2,1-b][1,3,4]thiadiazole 5b (NSC D-96022/1) was found to be the most active candidate of the series at five dose level screening with degree of selectivity toward Leukemic cancer cell line.
110 citations
TL;DR: In this article, a simple and practical procedure for the aqueous phase preparation of thiazoles and aminothiazoles has been developed from phenacyl bromides and thioamide/thiourea in the presence of β-cyclodextrin.
103 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2025 | 4 |
| 2024 | 9 |
| 2023 | 15 |
| 2022 | 25 |
| 2021 | 13 |
| 2020 | 14 |