TL;DR: Each strain displayed a specific response pattern to those products, according to the high variability previously described for this species, and strains were different from one another with regard to their level of aggressiveness against leaves detached from sherry grapevine vineyards.
Abstract: Botrydial and dihidrobotrydial are two characteristic metabolites of the phytopathogenic fungus Botrytis cinerea, which are involved in the development of necrotic lesions on grapevine and tobacco. Patchoulol and globulol, two natural products which are analogues to precursors of botrydial and dihidrobotrydial, were tested on 10 B. cinerea strains which were isolated from different hosts and varied in aggressiveness on grapevine leaves. Mycelial growth of all strains was prevented when they were grown on either patchoulol- or globulol-amended malt agar media (200 μg/μl). Each strain displayed a specific response pattern to those products, according to the high variability previously described for this species. Furthermore, strains were different from one another with regard to their level of aggressiveness against leaves detached from sherry grapevine vineyards.
Unterschiedliches Myzelwachstum verschiedener Botrytis-cinerea-Stamme auf Medien, die Patchoulol oder Globulol enthielten
Botrydial und Dihydrobotrydial sind zwei charakteristische Metaboliten des phytopathogenen Pilzes Botrytis cinerea; sie sind an der Entstehung nekrotischer Lasionen an Weinreben und Tabak beteiligt. Patchoulol und Globulol – naturliche Produkte, die analog zu Vorstufen von Botrydial und Dihydrobotrydial sind – wurden an 10 B.-cinerea-Stammen getestet, die von verschiedenen Wirtspflanzen stammten und auf Weinblattern unterschiedlich aggressiv waren. Das Myzelwachstum aller Stamme wurde vollstandig gehemmt, wenn sie auf MA-Medien gehalten wurden, denen Patchoulol oder Globulol (200 μg/μl) zugesetzt worden war. Jeder Stamm zeigte eine spezifische Reaktion auf diese Produkte, was der bei dieser Art bekannten hohen Variabilitat entspricht. Die Stamme unterschieden sich auch bezuglich des Ausmases ihrer Aggressivitat auf abgetrennten Blattern von Weinreben, deren Beeren zur Weinbranderzeugung genutzt werden.
TL;DR: The antifungal activity of natural sesquiterpenoids patchoulol, ginsenol, cedrol and globulol against the fungus Botrytis cinerea has been determined as mentioned in this paper.
Abstract: The antifungal activity of natural sesquiterpenoids patchoulol, ginsenol, cedrol and globulol against the fungus Botrytis cinerea has been determined. The diminishing of the effect after 3–6 days suggests that a mechanism of detoxification is present. Biotransformation of these fungistatic compounds has been investigated as a method of studying this mechanism.