TL;DR: Antenatal couple counseling may be a useful strategy to promote HIV-1 prevention interventions, and partner participation in VCT and couple counseling increased uptake of nevirapine and formula feeding.
Abstract: To determine effect of partner involvement and couple counseling on uptake of interventions to prevent HIV-1 transmission, women attending a Nairobi antenatal clinic were encouraged to return with partners for voluntary HIV-1 counseling and testing (VCT) and offered individual or couple posttest counseling. Nevirapine was provided to HIV-1-seropositive women and condoms distributed to all participants. Among 2104 women accepting testing, 308 (15%) had partners participate in VCT, of whom 116 (38%) were couple counseled. Thirty-two (10%) of 314 HIV-1-seropositive women came with partners for VCT; these women were 3-fold more likely to return for nevirapine (P = 0.02) and to report administering nevirapine at delivery (P = 0.009). Nevirapine use was reported by 88% of HIV-infected women who were couple counseled, 67% whose partners came but were not couple counseled, and 45%whose partners did not present for VCT (P for trend = 0.006). HIV-1-seropositive women receiving couple counseling were 5-fold more likely to avoid breast-feeding (P = 0.03) compared with those counseled individually. Partner notification of HIV-1-positive results was reported by 138 women (64%) and was associated with 4-fold greater likelihood of condom use (P = 0.004). Partner participation in VCT and couple counseling increased uptake of nevirapine and formula feeding. Antenatal couple counseling may be a useful strategy to promote HIV-1 prevention interventions.
TL;DR: The evolution of the global response to the epidemic, and the importance of redefining HIV/AIDS in Africa as a public health and infectious disease emergency are discussed.
TL;DR: It is found that meeting sexual partners through the Internet was associated with acquisition of syphilis among gay men and public health efforts must continually adapt disease control procedures to new venues.
Abstract: ContextA recent outbreak of syphilis among users of an Internet chat room challenged
traditional methods of partner notification and community education because
locating information on sexual partners was limited to screen names and privacy
concerns precluded identifying sexual partners through the Internet service
provider.ObjectivesTo determine the association of Internet use and acquisition of syphilis
and to describe innovative methods of partner notification in cyberspace.Design, Setting, and PatientsOutbreak investigation conducted at the San Francisco (Calif) Department
of Public Health (SFDPH) in June-August 1999 of 7 cases of early syphilis
among gay men linked to an online chat room; case-control study of 6 gay men
with syphilis reported to SFDPH in July-August 1999 (cases) and 32 gay men
without syphilis who presented to a city clinic in April-July 1999 (controls).Main Outcome MeasuresAssociation of syphilis infection with Internet use, Internet use among
cases vs controls, and partner notification methods and partner evaluation
indexes.ResultsDuring the outbreak, cases were significantly more likely than controls
to have met their sexual partners through use of the Internet (67% vs 19%;
odds ratio, 8.7; P = .03). We notified and confirmed
testing for 42% of named partners; the mean number of sexual partners medically
evaluated per index case was 5.9.ConclusionsIn this study, meeting sexual partners through the Internet was associated
with acquisition of syphilis among gay men. Public health efforts must continually
adapt disease control procedures to new venues, carefully weighing the rights
to privacy vs the need to protect public health.
TL;DR: The results showed that STI-related stigma directly and indirectly affected willingness to be treated for STI at public health clinics and Stigma transference emerged as a potent disincentive to treatment.
TL;DR: Involving index patients in shared responsibility for the management of sexual partners improves outcomes and health professionals should consider the following strategies for themanagement of individual patients: patient delivered partner therapy, home sampling for partners, and providing additional information for partners.
Abstract: Objective To examine the effectiveness of methods to improve partner notification by patient referral (index patient has responsibility for informing sex partners of their exposure to a sexually transmitted infection). Design Systematic review of randomised trials of any intervention to supplement simple patient referral. Data sources Seven electronic databases searched (January 1990 to December 2005) without language restriction, and reference lists of retrieved articles. Review methods Selection of trials, data extraction, and quality assessment were done by two independent reviewers. The primary outcome was a reduction of incidence or prevalence of sexually transmitted infections in index patients. If this was not reported data were extracted according to a hierarchy of secondary outcomes: number of partners treated; number of partners tested or testing positive; and number of partners notified, located, or elicited. Random effects meta-analysis was carried out when appropriate. Results 14 trials were included with 12 389 women and men diagnosed as having gonorrhoea, chlamydia, non-gonococcal urethritis, trichomoniasis, or a sexually transmitted infection syndrome. All studies had methodological weaknesses that could have biased their results. Three strategies were used. Six trials examined patient delivered partner therapy. Meta-analysis of five of these showed a reduced risk of persistent or recurrent infection in patients with chlamydia or gonorrhoea (summary risk ratio 0.73, 95% confidence interval 0.57 to 0.93). Supplementing patient referral with information for partners was as effective as patient delivered partner therapy. Neither strategy was effective in women with trichomoniasis. Two trials found that providing index patients with chlamydia with sampling kits for their partners increased the number of partners who got treated. Conclusions Involving index patients in shared responsibility for the management of sexual partners improves outcomes. Health professionals should consider the following strategies for the management of individual patients: patient delivered partner therapy, home sampling for partners, and providing additional information for partners.