Topic
Palindromic sequence
About: Palindromic sequence is a research topic. Over the lifetime, 999 publications have been published within this topic receiving 47350 citations. The topic is also known as: palindrome.
Papers published on a yearly basis
Papers
TL;DR: The complete nucleotide sequence of the adeno-associated virus 2 genome was determined and genome segments were assigned that code for three major viral capsid proteins and, possibly, some as-yet-unidentified, nonstructural viral proteins.
Abstract: The complete nucleotide sequence of the adeno-associated virus 2 genome was determined The single-stranded genome is 4,675 nucleotides in length and contains inverted terminal repeats of 145 nucleotides, the first 125 nucleotides of which form a palindromic sequence Within the inverted terminal repetitions, there are two distinct sequences representing an inversion of 43 nucleotides that can exist on either terminus The 5' and 3' termini of three major mRNA transcripts, which are present in both spliced and unspliced forms, were also mapped on the viral genome Potential initiation and termination codons for efficient protein synthesis were identified, and genome segments were assigned that code for three major viral capsid proteins and, possibly, some as-yet-unidentified, nonstructural viral proteins
848 citations
TL;DR: Isolates which had been postulated to beclosely related bymultilocus enzyme electrophoresis alsorevealed similar REP andERICPCR patterns, suggesting that theREP andERicPCR sequences are closely related.
Abstract: Thedistribution ofdispersed repetitive DNA (repetitive extragenic palindromic [REP]andenterobacterial repetitive intergenic consensus[ERIC]) sequencesinthegenomesofa numberofgram-negative soil bacteria was examined byusing conserved primers corresponding toREP andERICsequencesandthepolymerase chain reaction (PCR). Thepatterns oftheresulting PCRproducts wereanalyzed on agarosegels andfoundto behighly specific foreachstrain. TheREPandERICPCR patterns ofa series ofRhizobium meliloti isolates, previously ordered ina phylogenetic treebased on allelic variations at14enzyme loci (B.D.Eardly, L.A. Materon, N.H.Smith, D.A.Johnson, M.D.Rumbaugh, andR.K.Selander, Appl.Environ. Microbiol. 56:187-194), were determined. Isolates whichhadbeenpostulated tobeclosely related bymultilocus enzyme electrophoresis alsorevealed similar REP andERICPCR patterns, suggesting thattheREP andERICPCR
804 citations
TL;DR: Biochemical and immunological data showed that this protein is HMG1, an evolutionarily conserved, essential, and abundant component of the nucleus, which points to a critical role for cruciform DNA conformations.
Abstract: Cruciform DNA, a non-double helix form of DNA, can be generated as an intermediate in genetic recombination as well as from palindromic sequences under the effect of supercoiling. Eukaryotic cells are equipped with a DNA-binding protein that selectively recognizes cruciform DNA. Biochemical and immunological data showed that this protein is HMG1, an evolutionarily conserved, essential, and abundant component of the nucleus. The interaction with a ubiquitous protein points to a critical role for cruciform DNA conformations.
632 citations
TL;DR: While the REP sequences do not appear to modulate differential gene expression within an operon, they can affect the expression of both upstream and downstream genes to a small extent, probably by affecting the rate of mRNA degradation.
620 citations
TL;DR: The transposable IFP2 element of Trichoplusia ni was originally isolated as a host DNA insertion in spontaneous FP mutants of Galleria mellonella or Autographa californica nuclear polyhedrosis viruses, but is not apparent in DNAs isolated from the TN-R2 cell line or the authors' laboratory colony of T. ni larvae, suggesting IFP1 was recently introduced into the T. Ni genome.
510 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2025 | 5 |
| 2024 | 6 |
| 2023 | 6 |
| 2022 | 16 |
| 2021 | 17 |
| 2020 | 14 |