Showing papers on "Osteomyelitis published in 1973"
TL;DR: Evidence suggests that bacterial osteomyelitis and synovitis in turkeys should be regarded as a single disease entity.
Abstract: Separate submissions of lame turkeys totaling 149 were reviewed over a 3-year period. Eighty-five (56%) were placed in the category of osteomyelitis and synovitis. Evidence suggests that bacterial osteomyelitis and synovitis in turkeys should be regarded as a single disease entity. Staphylococcus aureus was the most common cause of the disease, followed by Escherichia coli. Intravenous injection of turkeys with E. coli and Staph. aureus produced osteomyelitis and synovitis indistinguishable from that in the spontaneous disease.
92 citations
TL;DR: This model closely resembles the human disease in which chronic osteomyelitis develops as a complication of internal fixation devices, and provides a reliable method for evaluating various specific approaches to the treatment of this difficult problem in management.
Abstract: The inoculation of Staphylococcus aureus into the tibial marrow cavity of rabbits following tibial fracture and rod insertion, as well as into the rodded tibia without fracture, results in chronic staphylococcal osteomyelitis in a high percentage of the animals. Staphylococci were easily recovered from the tibial marrow cavity for as long as eighteen months after onset of the infection. This model closely resembles the human disease in which chronic osteomyelitis develops as a complication of internal fixation devices, and provides a reliable method for evaluating various specific approaches to the treatment of this difficult problem in management.
82 citations
TL;DR: More than 30 years ago Michael Bonfiglio, with Thomas Lange and Young Kim, published this classic paper on osteomyelitis of vertebrae with secondary disc space infections, which clarified the pathogenesis of discspace infections and outlined problems associated with diagnosis and treatment.
Abstract: More than 30 years ago Michael Bonfiglio, with Thomas Lange and Young Kim, published this classic paper on osteomyelitis of vertebrae with secondary disc space infections. Dr. Bonfiglio and his associates had studied this condition in 21 children and 32 adults, one of the largest series recorded. He clarified the pathogenesis of disc space infections and outlined problems associated with diagnosis and treatment. Dr. Bonfiglio was born in Milwaukee, WI in 1917. He received his degree in medicine from the University of Chicago. While he was an intern there, working with children suffering through one of the polio epidemics inspired him to become an orthopedic surgeon. He spent most of his career at the University of Iowa. He died in 1995 and was memorialized in the Journal of Bone and Joint Surgery that year.
75 citations
TL;DR: Individuals with sickle-cell disease may develop gout, septic arthritis, osteomyelitis, aseptic osteonecrosis, and possibly hemarthrosis.
Abstract: Individuals with sickle-cell disease may develop gout, septic arthritis, osteomyelitis, aseptic osteonecrosis, and possibly hemarthrosis. Other patients have only arthralgia or joint effus...
68 citations
TL;DR: Five patients receiving regular hemodialysis developed osteomyelitis and Rib and thoracic vertebral column were the most common sites of involvement.
Abstract: Five patients receiving regular hemodialysis developed osteomyelitis. Rib and thoracic vertebral column were the most common sites of involvement. The diagnosis was made ante mortem in fou...
51 citations
TL;DR: Six of these eight patients with infections caused by HB bacteria had deep tissue abscesses including empyema, meningitis, peritonitis, and osteomyelitis and treatment with tetracycline or chloramphenicol should be instituted until susceptibility studies are available.
45 citations
TL;DR: Hyperbaric oxygenation from the study reported here appears to offer a new type of treatment for these resistant cases of osteomyelitis.
Abstract: Hyperbaric oxygen was used in the treatment of intractable osteomyelitis of the mandible. Dentists are frequently called on to manage postoperative bone infections. In spite of comprehensive antibiotic therapy, the occurrence of osteomyelitis after tooth extraction is not infrequent. The dentist is then faced with management of an intractable infection of the bone that seems to resist all conventional therapy. Hyperbaric oxygenation from the study reported here appears to offer a new type of treatment for these resistant cases of osteomyelitis.
38 citations
TL;DR: It is concluded that TMP-SMZ is effective in the treatment of acute brucellosis and in some special forms such as osteomyelitis and endocarditis, and longer duration of treatment and the higher initial doses seem warranted to improve results and prevent recurrences.
Abstract: A clinical trial of the combination of trimethoprim and sulfamethoxazole (TMPSMZ), was conducted in 86 patients with brucellosis, hospitalized either in Trikala (Thessaly) or in Athens. All cases had the typical clinical picture of acute brucellosis, or that of special localizations and high titers of agglutination reactions in their sera. In 39 patients the diagnosis was confirmed by positive blood cultures. There were 14 cases of osteoarthritic localization, one severe case of brucella endocarditis, and two cases of epididymo-orchitis. Clinical response to the drug was good in 78 cases, with defervescence ensuing within two to eight days. In eight cases the response was not satisfactory. Relapses occurred in 4% of all cases. Bacteriologic response was observed in 19 of 39 patients. In 15 patients the blood ;culture remained positive although the clinical response was good. There were five patients who initially had a negative blood culture, and later a positive culture. Dosage varied from four to six tablets, occasionally eight tablets daily. Duration of treatment was generally one month at first, and subsequently two months. It is concluded that TMP-SMZ is effective in the treatment of acute brucellosis and in some special forms such as osteomyelitis and endocarditis. Longer duration of treatment and the higher initial doses seem warranted to improve results and prevent recurrences.
32 citations
TL;DR: Cephaloridine intramuscularly and cephalexin orally were given sequen tially at dosages of 100 mg or 200 mg/kg/day for 28 days to 56 days in the treatment of 14 children with acute staphylococcal osteomyelitis and all patients recovered completely.
Abstract: Cephaloridine intramuscularly and cephalexin orally were given sequen tially at dosages of 100 mg or 200 mg/kg/day for 28 days to 56 days in the treatment of 14 children with acute staphylococcal osteomyelitis. All patients recovered completely. No adverse effects were detected at either dosage schedule. The average duration of hospitalization was 13 days.
30 citations
TL;DR: This case is reported to alert clinicians to such heroinrelated infections, which have been rare and are likely to be caused by organisms of low virulence.
Abstract: Excerpt To the editor: Fungal osteomyelitis, especially when caused by organisms of low virulence, has been rare. This case is reported to alert clinicians to such heroinrelated infections, which m...
Journal Article•
TL;DR: Bone scanning was found to be important in the early detection of hematogenous osteomye hue in the presence of negative x-rays and is recommended as a screening procedure in cases of somatic complaints referable to the skeletal system in which intravenous drug abuse is suspected.
TL;DR: Subperiosteal claviculectomy and methicillin produced a cure for osteomyelitis of the clavicle after an indwelling catheter had been used in the subclavian vein to treat postoperative staphylococcal bacteremia and wound infection following repair of a hiatus hernia.
Abstract: A patient developed osteomyelitis of the clavicle after an indwelling catheter had been used in the subclavian vein for eight days. The catheter had been employed to administer ampicillin sodium and methicillin sodium to treat postoperative staphylococcal bacteremia and wound infection following repair of a hiatus hernia. Subperiosteal claviculectomy and methicillin produced a cure.
TL;DR: A 23-year-old Negro man who was known to have had sarcoidosis for 2.5 years and was being treated with corticoids experienced pain beneath the left scapula, and radiographs revealed pulmonary infiltrates and changes of osteomyelitis in the rib.
Abstract: A 23-year-old Negro man who was known to have had sarcoidosis for 2.5 years and was being treated with corticoids experienced pain beneath the left scapula. Radiographs revealed pulmonary infiltrates and changes of osteomyelitis in the rib. Cryptococcus neoformans was cultured from pus aspirated from a mass in the left chest posteriorly. Fifteen other patients who had both diseases have been reported; 8 had been treated with corticosteroids, in only 3 of whom, the cryptococcal infection was probably not causally related to administration of the steroids. It is suggested that sarcoidosis predisposes to cryptococcosis.
TL;DR: Two cases of squamous epithelial cancer and one of reticular cell sarcoma in chronic fistulating osteitis are described and malignant degeneration should always be suspected when there is a change in the clinical pattern in cases of chronic fistulate osteitis.
Abstract: SUMMARY Two cases of squamous epithelial cancer and one of reticular cell sarcoma in chronic fistulating osteitis are described. Malignant degeneration should always be suspected when there is a change in the clinical pattern in cases of chronic fistulating osteitis and histological investigation should routinely be performed. REFERENCES Buxton, R. St. J. (1954) Malignant change in sinuses resulting from osteomyelitis. Dalmonte, A. (1953) Neoplasie in proccssi osteomielitici. Chir. Organi Moo. 38, Hejna, W. F. (1965) Squamous-cell carcinoma developing in the chronic draining Heilmann, D. (1957) Plasmozytom auf dem Boden einer chronischen Osteomyclitis Sedlin, E. D. & Fleming, J. L. (1963) Epidcrmoid carcinomas arising in chronic Schiewe, R. & Koch, W. (1967) Zur Malignitiit des osteomyelitischen Fistelkarzi- Med. Press 232, 45. 252. sinuses of osteomyelitis. Cancer 18, 128. bei gleichzeitiger ostcitis deformans Paget. Miinchen med.
TL;DR: Presentation of a mass lesion without constitutional signs signifying an infectious etiology is the primary problem associated with the two cases of primary sternal osteomyelitis.
TL;DR: In this article, the anti-gamma-lysin was present in the serum of most of the 19 patients with proven staphylococcal osteomyelitis studied here.
Abstract: The anti-alpha-haemolysin test is widely used in the diagnosis of staphylococcal osteomyelitis. An additional test would be welcomed because raised antibodies to this antigen are not seen in all proven cases. This communication reports that anti-gamma-lysin was present in the serum of most of the 19 patients with proven staphylococcal osteomyelitis studied here. In two cases followed up after chemotherapy was initiated both tests indicated the satisfactory progress of the patient.
1 Jan 1973
TL;DR: It is reported that anti-gamma-lysin was present in the serum of most of the 19 patients with proven staphylococcal osteomyelitis studied here and indicated the satisfactory progress of the patient.
Abstract: SYNOPSISTheanti-alpha-haemolysin testiswidely usedinthediagnosis ofstaphylococcal osteomyelitis. Anadditional testwouldbewelcomed because raised antibodies tothis antigen arenot seeninall provencases.Thiscommunication reports thatanti-gamma-lysin was present inthe serum ofmostofthe19patients with provenstaphylococcal osteomyelitis studied here. Intwocases followed up after chemotherapy was initiated bothtests indicated thesatisfactory progressofthe
TL;DR: During treatment for a painful sickle cell crisis, a patient developed jaw pain that was diagnosed as osteomyelitis and the lesion resisted all forms of treatment but resolved after five months of surgical treatment and antibiotic therapy.
Abstract: During treatment for a painful sickle cell crisis, a patient developed jaw pain that was diagnosed as osteomyelitis. It is thought that his pain and subsequent lesion were caused by the obstruction of the capillaries of the mandible by sickled erythrocytes. The lesion resisted all forms of treatment but resolved after five months of surgical treatment and antibiotic therapy.
TL;DR: Twelve patients had acute blastomycotic arthritis without evidence of adjacent osteomyelitis, and the method of spread appeared to be hematogenous.
Abstract: Twelve patients had acute blastomycotic arthritis without evidence of adjacent osteomyelitis. The method of spread appeared to be hematogenous. All patients in this series had pulmonary involvement, and 11 had skin lesions. The diagnosis was established by microscopic examination of the joint fluid and confirmed by culture. Intravenous administration of amphotericin B was the treatment of choice.
TL;DR: This type of pyogenic osteomyelitis usually responds to antibiotic therapy provided that the involved intestine and associated fistulas and abscesses are removed.
Abstract: Osteomyelitis of the ilium complicating Crohn’s disease is reported in 4 patients. This represents an incidence of 2 per cent in the material examined by the author.In each instance fistulous tracts and abscesses were present adjacent to the involved iliac wings.This type of pyogenic osteomyelitis usually responds to antibiotic therapy provided that the involved intestine and associated fistulas and abscesses are removed.