Topic
NADPH binding
About: NADPH binding is a research topic. Over the lifetime, 315 publications have been published within this topic receiving 10453 citations.
Papers published on a yearly basis
Papers
TL;DR: These resting state and inhibited humanCatalase structures support specific, structure-based mechanisms for the catalase substrate recognition, reaction and inhibition and provide a molecular basis for understanding ethanol intoxication and the likely effects of human polymorphisms.
475 citations
TL;DR: These findings confirm the recent description of the membrane-bound cytochrome b as a FAD-containing flavocy tochrome b containing the NADPH binding site, and implicate the three cytosolic proteins in its activation.
274 citations
TL;DR: New details of NADPH binding to Lactobacillus casei dihydrofolate reductase have become visible as a result of crystallographic refinement to an R factor of 0.152 at 1.7 A resolution.
250 citations
TL;DR: The results suggest that thioredoxin reductase must undergo conformational changes during enzyme catalysis, and no direct evidence is available as yet for such conformational change.
221 citations
TL;DR: The activation domain of p67 phox regulates the reduction of FAD but has only a small effect on NADPH binding, consistent with a dominant effect on hydride/electron transfer from NADPH to FAD.
212 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2021 | 5 |
| 2020 | 4 |
| 2019 | 4 |
| 2018 | 11 |
| 2017 | 2 |
| 2016 | 2 |