Topic
Membrane coat
About: Membrane coat is a research topic. Over the lifetime, 143 publications have been published within this topic receiving 5866 citations.
Papers published on a yearly basis
Papers
TL;DR: In vitro synthesis of endoplasmic reticulum-derived transport vesicles has been reconstituted with washed membranes and three soluble proteins and it is proposed that the coat structures be called COPI and COPII.
1,385 citations
TL;DR: The fusion tube–generated membrane network signals the end of the first stage of cell plate formation, a series of steps that both mechanically stabilizes the initial delicate, interwoven membrane network and then transforms it into two new plasma membranes and a new cell wall.
432 citations
TL;DR: Results indicate that the Sar1-Sec23-Sec24 prebudding complex is sufficient to form cargo-containing tubules in vivo, whereas the Sec13-Sec31 complex is required for membrane fission.
194 citations
TL;DR: Cryo-electron tomography results reveal the molecular architecture of the cilium and provide insights into protein functions and suggest that the ciliary rootlet is involved in cellular transport and stabilizes the axoneme.
163 citations
TL;DR: Compartmentalized bacteria have proteins that are structurally related to eukaryotic membrane coats, and one of these proteins localizes at the membrane of vesicles formed inside bacterial cells.
Abstract: The development of the endomembrane system was a major step in eukaryotic evolution. Membrane coats, which exhibit a unique arrangement of β-propeller and α-helical repeat domains, play key roles in shaping eukaryotic membranes. Such proteins are likely to have been present in the ancestral eukaryote but cannot be detected in prokaryotes using sequence-only searches. We have used a structure-based detection protocol to search all proteomes for proteins with this domain architecture. Apart from the eukaryotes, we identified this protein architecture only in the Planctomycetes-Verrucomicrobia-Chlamydiae (PVC) bacterial superphylum, many members of which share a compartmentalized cell plan. We determined that one such protein is partly localized at the membranes of vesicles formed inside the cells in the planctomycete Gemmata obscuriglobus. Our results demonstrate similarities between bacterial and eukaryotic compartmentalization machinery, suggesting that the bacterial PVC superphylum contributed significantly to eukaryogenesis.
150 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2021 | 3 |
| 2020 | 2 |
| 2019 | 9 |
| 2018 | 10 |
| 2017 | 10 |
| 2016 | 26 |