Topic
Marein
About: Marein is a research topic. Over the lifetime, 11 publications have been published within this topic receiving 303 citations.
Papers
TL;DR: This work represents the first recorded example of the isolation of compounds 1–3, 6, 7, 9, 11, and 12 from C. tinctoria, which support the medicinal use of this plant in the prevention of cardiovascular diseases.
Abstract: Three new phenolic compounds, coretinphenol (1), coretincone (2), and coretinphencone (3), were isolated from the buds of Coreopsis tinctoria Nutt., together with nine known compounds, including butein (4), okanin (5), isoliquiritigenin (6), maritimetin (7), taxifolin (8), isookanin (9), marein (10), sachalinoside B (11), and 2-phenylethyl-β-d-glucoside (12). The chemical structures of these compounds were elucidated by extensive spectroscopic analysis and on the basis of their chemical reactivity. This work represents the first recorded example of the isolation of compounds 1–3, 6, 7, 9, 11, and 12 from C. tinctoria. Compounds 5–9 showed strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity, with IC50 values of 3.35 ± 0.45, 9.6 ± 2.32, 4.12 ± 0.21, 6.2 ± 0.43, and 7.9 ± 0.53 μM, respectively. Compounds 2 and 8 exhibited angiotensin I-converting enzyme inhibitory activity, with IC50 values of 228 ± 4.47 and 145.67 ± 3.45 μM, respectively. The activities of phenolic compounds isolated from C. tinctoria support the medicinal use of this plant in the prevention of cardiovascular diseases.
86 citations
TL;DR: Caspase 3/7 activation measurements show that Coreopsis tinctoria flowering tops extracts, as well as marein and flavanomarein, significantly inhibit apoptosis, and not through a decrease on superoxide radical production.
53 citations
TL;DR: Flavonoid C1 from C. tinctoria was protective in experimental AP and this effect may at least in part be attributed to its antioxidant effects by activation of Nrf2-mediated pathways, which suggest the potential utilisation of C. Tinctoria to treat AP.
48 citations
TL;DR: NMR spectral data for okanin 4'- O-beta- D-glucoside (marein) are given and their structures have been elucidated by means of UV, FD-MS, (1)H-N MR, and (13)C-NMR spectroscopy.
Abstract: Okanin 4'- O-beta- D-(2'',4'',6''-triacetyl)-glucoside, okanin 4'- O-beta- D-(6''- TRANS-P-coumaroyl)-glucoside, both new natural compounds, and okanin 3'- O-beta- D-glucoside have been isolated from the leaves of BIDENS PILOSA L. Their structures have been elucidated by means of UV, FD-MS, (1)H-NMR, and (13)C-NMR spectroscopy. NMR spectral data for okanin 4'- O-beta- D-glucoside (marein) are given.
47 citations
TL;DR: Chlorogenic acid, 3,5-dicaffeoylquinic acid and luteolin-7-O-glucoside largely contributing to cellular antioxidant activity of 'Qiju' by forming protective membrane around erythrocyte should be markers for quality control of ' Qiju'.
45 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2019 | 2 |
| 2018 | 1 |
| 2016 | 1 |
| 2015 | 1 |
| 2013 | 1 |
| 2012 | 1 |