Topic
Lymph Node Pain
About: Lymph Node Pain is a research topic. Over the lifetime, 4 publications have been published within this topic receiving 245 citations.
Papers
TL;DR: The dosimetric calculations show that further optimization is advisable to increase the efficacy and reduce possible long-term toxicity in α-particle therapy in epithelial ovarian cancer, and that a lower specific activity is associated with a lower single-cell dose, whereas a high specific activity may result in a lower central dose in microtumors.
Abstract: 1073 Objectives: Kikuchi-Fujimoto disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a rare cause of lymphadenopathy with a highe prevalence in Asia. It can involve systemic lymph nodes, with cervical lymph nodes most commonly affected, and is easily misdiagnosed as lymphoma. This study investigated 18F-FDG PET/CT findings in KFD, and its usefulness for differential diagnosis from non-Hodgkin lymphoma (NHL).Methods: Three groups of patients [10 KFD, 12 indolent lymphoma (IL) and 15 aggressive lymphoma (AL)] underwent 18F-FDG PET/CT scan. Two experienced nuclear medicine physician independently interpreted the images and recorded the areas, size, and SUVmax and SULmax of lymph nodes involved. Possible organ involvements or other hypermetabolic lesions were also analyzed. Some serological indicators were collected.Results: The median age of KFD group was 23 (13-56) years old, with 8 women included. There were 9 cases with fever, 10 with lymph node enlargement, 3 with lymph node pain, 5 with skin rash, 5 with pharyngalgia, 3 with muscle pain, 5 with arthralgia and 1 with subcutaneous nodules of lower limbs. The course of disease was 31 (10-185) days. Leukocyte count was 8.4 (1.3-13.8)×109/L, neutrophil count 5.2 (0.8-12.6)×109/L, LDH 463.5 (188-1123) U/L, ESR 45 (4-101) mm/H, CRP 21.6 (11.5-101.8) mg/L, ALT 27 (11-273) U/L, AST 39.5 (21-276) U/L. At least two lymph node regions were involved in all participates, including neck in 10 cases, axilla in 9 cases, mediastinum in 8 cases, abdomen in 7 cases, pelvic in 6 cases and groin in 6 cases. The largest lymph node was 22 (13-36) mm, lymph node SUVmax 8.4 (6-19.2), highest SULmax 9.9 (4.9-15.2), liver SUVmax 2.8 (1.8-3.3), spleen size 9 (6-10) costal units, spleen SUVmax 3.4 (2.1-4.7), and bone marrow SUVmax 4.3 (3.1-5.4). High metabolic focis were found in 1 case of subcutaneous nodule with SUVmax 3.5, 2 cases of skin lesion with SUVmax 2.1 and 3.2, and 1 case of muscle lesion with SUVmax 2.1. The density of lymph nodes was uneven in 2 cases and blurred in 2 cases, which were confirmed by ultrasound. The correlation analysis showed that SUVmax of lymph nodes was correlated with LDH (r=-0.927, p
66 citations
TL;DR: In this study, 134 patients with neck lymphadenopathy in the five years from April 2005 to March 2010 were included, and the disease was inflammatory in 109 patients and malignant in 25 patients, with the suffering period longer in the malignant group than in the inflammatory group.
Abstract: The purpose of this study was to investigate neck lymphadenopathy patients in our hospital, and to investigate items requiring attention on the occasion of examination of these patients. In this study, 134 patients with neck lymphadenopathy in the five years from April 2005 to March 2010 were included. The kind of diseases, the period of suffering (the period from onset to consultation), relationship with pain, radiological examination, fine needle aspiration cytology and lymph node biopsy findings were examined. Of 134 patients, the disease was inflammatory in 109 patients (81.3%) and malignant in 25 patients (18.7%). The suffering period was longer in the malignant group than in the inflammatory group. Furthermore, the inflammatory group had more patients with neck lymph node pain than the malignant group, and the group with the short suffering period had more patients with neck lymph node pain than that with the long suffering period. Fine needle aspiration cytology was performed in 36 patients (26.9%), and finally, all of the seven patients with class III were diagnosed as having malignant disease. A neck lymph node biopsy was performed in 38 patients (28.4%), and four of 38 patients were diagnosed as having metastatic carcinoma. Two patients in the inflammatory group and two patients in the malignant group took more than 90 days to reach a definite diagnosis. Many kind of diseases cause neck lymphadenopathy, and, therefore, it is important to perform a neck lymph node biopsy immediately, if it is difficult to establish a diagnosis.
5 citations
TL;DR: Children who met fibromyalgia criteria had a statistically greater degree of subjective muscle pain, sleep disturbance, and neurological symptoms than did those who did not meet the fibromy arthritis criteria.
Abstract: Chronic fatigue syndrome (CFS) and primary juvenile fibromyalgia syndrome (PJFS) are illnesses with a similar pattern of symptoms of unknown etiology. Twenty-seven children for whom CFS was diagnosed were evaluated for fibromyalgia by the presence of widespread pain and multiple tender points. Eight children (29.6%) fulfilled criteria for fibromyalgia. Those children who met fibromyalgia criteria had a statistically greater degree of subjective muscle pain, sleep disturbance, and neurological symptoms than did those who did not meet the fibromyalgia criteria. There was no statistical difference between groups in degree of fatigue, headache, sore throat, abdominal pain, depression, lymph node pain, concentration difficulty, eye pain, and joint pain. CFS in children and PJFS appear to be overlapping clinical entities and may be indistinguishable by current diagnostic criteria.
TL;DR: Ten patients with recurrent squamous cell carcinoma of the head and neck received daily injections of interleukin‐2 from the Jurkat T‐cell line purified by high pressure liquid chromatography, and IL‐2 was ineffective in two patients who had already undergone functional or radical neck dissection.
Abstract: Ten patients with recurrent squamous cell carcinoma of the head and neck received daily injections of interleukin-2 (IL-2) from the Jurkat T-cell line purified by high pressure liquid chromatography for 10 days. Two hundred units of IL-2 in 0.5 ml were injected 1.5 cm from the insertion of the sternocleidomastoid muscle on the mastoid. When possible, courses were repeated at 45-day intervals. IL-2 was ineffective in two patients who had already undergone functional or radical neck dissection. By contrast, in six patients with contralateral or bilateral cervical lymph nodes, complete or partial disappearance of the tumor was observed. The injections were occasionally followed by moderate local swelling and lymph node pain, but no systemic disturbances.
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2019 | 1 |
| 2012 | 1 |
| 1994 | 1 |
| 1988 | 1 |