About: LRRN3 is a research topic. Over the lifetime, 1 publications have been published within this topic. The topic is also known as: FIGLER5 & NLRR-3.
TL;DR: Although LRRN3 plays an essential role in the development of neural system, little is know about its function, mechanism as well as clinical significance.
Abstract: As a member of neural leucine-rich repeat protein family,LRRN3 is an evolutionarily conserved transmembrane protein with diverse functionsLRRN3 is composed of a number of consecutive LRR do-mains,fibronectin type Ⅲ-like domain(FNⅢ) and immunoglobulin-like C2 type domain(IgC2)It regulates the development of neural system through mediating cell adhesionIt has been well demonstrated that LR-RN3 not only participates in neural development,differentiation and damage repair,but also relates to the occurrence of mental disorders such as autismAlthough LRRN3 plays an essential role in the development of neural system,little is know about its function,mechanism as well as clinical significanceThe structure and function of LRRN3 as well as its relationship with human diseases are reviewed