About: Kefir is a research topic. Over the lifetime, 693 publications have been published within this topic receiving 14837 citations. The topic is also known as: Kephir & keefir.
TL;DR: Based on stoichiometry studies and the high levels of NAD-linked 1,2-propanediol-dependent oxidoreductase, a novel pathway for anaerobic lactic acid degradation is proposed and suggests it plays a role in maintaining cell viability.
Abstract: The degradation of lactic acid under anoxic conditions was studied in several strains of Lactobacillus buchneri and in close relatives such as Lactobacillus parabuchneri, Lactobacillus kefir, and Lactobacillus hilgardii. Of these lactobacilli, L. buchneri and L. parabuchneri were able to degrade lactic acid under anoxic conditions, without requiring an external electron acceptor. Each mole of lactic acid was converted into approximately 0.5 mol of acetic acid, 0.5 mol of 1,2-propanediol, and traces of ethanol. Based on stoichiometry studies and the high levels of NAD-linked 1, 2-propanediol-dependent oxidoreductase (530 to 790 nmol min(-1) mg of protein(-1)), a novel pathway for anaerobic lactic acid degradation is proposed. The anaerobic degradation of lactic acid by L. buchneri does not support cell growth and is pH dependent. Acidic conditions are needed to induce the lactic-acid-degrading capacity of the cells and to maintain the lactic-acid-degrading activity. At a pH above 5.8 hardly any lactic acid degradation was observed. The exact function of anaerobic lactic acid degradation by L. buchneri is not certain, but some results indicate that it plays a role in maintaining cell viability.
TL;DR: The History of Feremented Foods, J.B. Prajapati and B.R. Nair Challenges Associated with the Development of Probiotic-Containing Functional Foods, N. Kearney, C. Stanton, and R.P. Ross The Properties of Enterococcus faecium and the Fermented Milk Product- Gaio(R), M. Farnworth Kefir-A Fermentation Milk Product.
Abstract: The History of Feremented Foods, J.B. Prajapati and B.M. Nair Challenges Associated with the Development of Probiotic-Containing Functional Foods, N. Kearney, C. Stanton, C. Desmond, M. Coakley, J.K. Collins, G. Fitzgerald, and R.P. Ross The Properties of Enterococcus faecium and the Fermented Milk Product- Gaio(R), M.C. Bertolami and E.R. Farnworth Kefir-A Fermented Milk Product, E.R. Farnworth and I. Mainville Yogurt and Immunity: The Health Benefits of Fermented Milk Products That Contain Lactic Acid Bacteria, J. Van de Water and P. Naiyanetr Health Properties of Milk Fermented with Lactobacillus. Casei strain Shirota (LcS), K. Miyazaki and T. Matsuzaki Biologically Active Peptides Released in Fermented Milk: Role and Functions, G. Vinderola, A. de Moreno de LeBlanc, G. Perdigon, and C. Matar Cheese and Its Potential As a Probiotic Food, K.J. Heller, W. Bockelmann, J. Schrezenmeir, and M. deVrese Natto: A Soybean Food Made by Fermenting Cooked Soybeans with Bacillus subtilis (natto), T. Hosoi and K. Kiuchi Fermented Meat, W.P. Hammes, D. Haller, and M.G. Ganzle Miso: Production, Properties, and Benefits to Health, Y. Minamiyama and S. Okada Korean Fermented Foods: Kimchi and Doenjang, J. Surh, Y.-K. L. Kim, and H.Kwon Lactobacillus plantarum: The Role in Foods and in Human mHealth, G. Molin Sauerkraut, W. Holzapfel, U. Schillinger, and H. Buckenhuskes New Trends of Table Olive Processing for Quality Control and Functional Proprieties, M. Hamdi Traditional Chinese Fermented Foods, Y-H.P. Hsieh, S. Pao, and J. Li Tempeh: A Mold-Modified Indigenous Fermented Food, D.Y.C. Fung and B.A. Crozier-Dodson Thai Fermented Foods: Microorganisms and Their Health Benefits, S. Tanasupawat and W. Visessanguan Production of Probiotic Cultures and Their Addition in Fermented Foods, C.P. Champagne and H. Mollgaard The Future for Fermented Foods, E.R. Farnworth Index
TL;DR: These reports have led to increased interest in kefir as a focus of research and as a potential probiotic-containing product, and a particular emphasis on the microbial composition and the health benefits of the product is placed.
Abstract: Kefir is a complex fermented dairy product created through the symbiotic fermentation of milk by lactic acid bacteria and yeasts contained within an exopolysaccharide and protein complex called a kefir grain. As with other fermented dairy products, kefir has been associated with a range of health benefits such as cholesterol metabolism and angiotensin-converting enzyme (ACE) inhibition, antimicrobial activity, tumor suppression, increased speed of wound healing, and modulation of the immune system including the alleviation of allergy and asthma. These reports have led to increased interest in kefir as a focus of research and as a potential probiotic-containing product. Here, we review those studies with a particular emphasis on the microbial composition and the health benefits of the product, as well as discussing the further development of kefir as an important probiotic product.
TL;DR: Along the pathway A→B→C, the streptococcal proportion in the total kefir microflora increased by 26–30% whereas the lactobacilli decreased by 13–23%.
Abstract: In an investigation of the changes in the microflora along the pathway: kefir grains (A)→kefir made from kefir grains (B)→kefir made from kefir as inoculum (C), the following species of lactic acid bacteria (83–90%) of the microbial count in the grains) were identified: Lactococcus lactis subsp lactis, Streptococcus thermophilus, Lactobacillus delbrueckii subsp bulgaricus, Lactobacillus helveticus, Lactobacillus casei subsp pseudoplantarum and Lactobacillus brevis Yeasts (10–17%) identified were Kluyveromyces marxianus var lactis, Saccharomyces cerevisiae, Candida inconspicua and Candida maris In the microbial population of kefir grains and kefir made from them the homofermentative lactic streptococci (52–65% and 79–86%, respectively) predominated Within the group of lactobacilli, the homofermentative thermophilic species L delbrueckii subsp bulgaricus and L helveticus (70–87% of the isolated bacilli) predominated Along the pathway A→B→C, the streptococcal proportion in the total kefir microflora increased by 26–30% whereas the lactobacilli decreased by 13–23% K marxianus var lactis was permanently present in kefir grains and kefirs, whereas the dominant lactose-negative yeast in the total yeast flora of the kefir grains dramatically decreased in kefir C Journal of Industrial Microbiology & Biotechnology (2002) 28, 1–6 DOI: 101038/sj/jim/7000186
TL;DR: Kefir and its constituents have antimicrobial, antitumor, anticarcinogenic and immunomodulatory activity and also improve lactose digestion, among others, and the status of a natural probiotic is designated as the 21th century yoghurt.