Topic
ITPase activity
About: ITPase activity is a research topic. Over the lifetime, 45 publications have been published within this topic receiving 1708 citations.
Papers
TL;DR: It is shown that inosine triphosphatase (ITPase) activity catalyzed by F1 from bovine heart mitochondria is much more sensitive to inactivation by 5'-p-fluorosulfonylbenzoyladenosine (FSBA) than is ATPase activity.
104 citations
TL;DR: Pretherapeutic screening of individuals for ITPA 94C>A polymorphisms in the Japanese population should be considered for safer and more tolerable treatment with thiopurine drugs.
80 citations
TL;DR: Two ITPA variants were strongly associated with protection against treatment‐related anemia in patients with genotype 2/3 HCV, but they did not decrease the need for RBV dose reduction or increase the rate of SVR.
76 citations
TL;DR: Reciprocal Michaelis-Menten constants obtained by optical means have been compared with those obtained chemically and some kinetic considerations concerning deformable enzyme systems are explored.
72 citations
TL;DR: It is argued convincingly that bi-site hydrolysis activity is negligible, and may not even exist, and that only tri-site Hydrolysis drives subunit rotation.
66 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2019 | 1 |
| 2018 | 4 |
| 2017 | 1 |
| 2016 | 3 |
| 2015 | 2 |
| 2014 | 2 |