About: Ionizing radiation is a research topic. Over the lifetime, 5601 publications have been published within this topic receiving 97024 citations. The topic is also known as: ionising radiation & radioactive radiation.
TL;DR: This annex is aimed at providing a sound basis for conclusions regarding the number of significant radiation accidents that have occurred, the corresponding levels of radiation exposures and numbers of deaths and injuries, and the general trends for various practices, in the context of the Committee's overall evaluations of the levels and effects of exposure to ionizing radiation.
Abstract: NOTE The report of the Committee without its annexes appears as Official Records of the General Assembly, Sixty-third Session, Supplement No. 46. The designations employed and the presentation of material in this publication do not imply the expression of any opinion whatsoever on the part of the Secretariat of the United Nations concerning the legal status of any country, territory, city or area, or of its authorities, or concerning the delimitation of its frontiers or boundaries. The country names used in this document are, in most cases, those that were in use at the time the data were collected or the text prepared. In other cases, however, the names have been updated, where this was possible and appropriate, to reflect political changes. Scientific Annexes Annex A. Medical radiation exposures Annex B. Exposures of the public and workers from various sources of radiation INTROdUCTION 1. In the course of the research and development for and the application of atomic energy and nuclear technologies, a number of radiation accidents have occurred. Some of these accidents have resulted in significant health effects and occasionally in fatal outcomes. The application of technologies that make use of radiation is increasingly widespread around the world. Millions of people have occupations related to the use of radiation, and hundreds of millions of individuals benefit from these uses. Facilities using intense radiation sources for energy production and for purposes such as radiotherapy, sterilization of products, preservation of foodstuffs and gamma radiography require special care in the design and operation of equipment to avoid radiation injury to workers or to the public. Experience has shown that such technology is generally used safely, but on occasion controls have been circumvented and serious radiation accidents have ensued. 2. Reviews of radiation exposures from accidents have been presented in previous UNSCEAR reports. The last report containing an exclusive chapter on exposures from accidents was the UNSCEAR 1993 Report [U6]. 3. This annex is aimed at providing a sound basis for conclusions regarding the number of significant radiation accidents that have occurred, the corresponding levels of radiation exposures and numbers of deaths and injuries, and the general trends for various practices. Its conclusions are to be seen in the context of the Committee's overall evaluations of the levels and effects of exposure to ionizing radiation. 4. The Committee's evaluations of public, occupational and medical diagnostic exposures are mostly concerned with chronic exposures of …
TL;DR: It has been concluded that the types and yields of damaged moieties produced in intracellular DNA by low LET ionizing radiation are consistent with the mechanisms of production that involve both OH radical attack and a direct ionization of the macromolecule.
Abstract: Publisher Summary This chapter provides a framework for understanding the way permanent heritable damage in cellular DNA results from exposure to ionizing radiation. If the processes that occur in the time between the initial radiation energy deposition and the formation of such damage can be described, then rationales can be developed for the modulation of radiation damage. For example, it may be possible to (1) devise a means of differentially modulating the amounts of radiation damage, for instance, in tumor versus normal tissue in radiotherapy, or (2) predict the effects of variations of several parameters on the biological consequences of a radiation dose. It has been concluded that the types and yields of damaged moieties produced in intracellular DNA by low LET ionizing radiation are consistent with the mechanisms of production that involve both OH radical attack and a direct ionization of the macromolecule. At the radiation-dose levels producing one lethal lesion per cell, the amounts of damage produced by ionizing radiation are several orders of magnitude lower than the amounts of damage required for equal kill by other agents. Individual damaged moieties are not biologically significant; they can easily be repaired using the undamaged DNA strand as a template. The lethal lesion produced in cellular DNA is a locally multiply damaged site.
TL;DR: In this paper, the authors present an Ionizing Radiation Sources and Biological Effects (IRBE) study, in which the sources and biological effects of ionizing radiation are investigated and compared.
Abstract: (1983). Ionizing Radiation: Sources and Biological Effects. International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine: Vol. 43, No. 5, pp. 585-586.