Topic
Intervertebral disk calcification
About: Intervertebral disk calcification is a research topic. Over the lifetime, 37 publications have been published within this topic receiving 608 citations.
Papers
TL;DR: Because of the high heritability of disk calcification, it is possible that an effective reduction in occurrence of severe disk herniation in Dachshunds could be obtained by selective breeding against high numbers of calcified disks at 2 years of age.
Abstract: Objective—To quantify the association between intervertebral disk calcification and disk herniation in Dachshunds. Design—Longitudinal study. Animals—61 Dachshunds that had been radiographically screened for calcification of intervertebral disks at 2 years of age in other studies. Thirty-seven of the dogs had survived to the time of the present study and were ≥ 8 years of age; 24 others had not survived. Procedures—Radiographic examination of 36 surviving dogs was performed, and information on occurrence of disk calcification at 2 years of age were obtained from records of all 61 Dachshunds. Information on occurrence of disk herniation between 2 and 8 years of age was obtained from owners via questionnaire. Associations between numbers of calcified disks and disk herniation were analyzed via maximum likelihood logistic regression. Results—Disk calcification at 2 years of age was a significant predictor of clinical disk herniation (odds ratio per calcified disk, 1.42; 95% confidence interval, 1.19 to 1.81)...
54 citations
TL;DR: From a careful review of the material, it would appear that certain aspects of the condition occur with sufficient frequency to merit consideration as a separate entity.
Abstract: Roentgenologic evidence of intervertebral disk calcification is infrequent in adult life; in childhood, it is an exceedingly uncommon finding. We have discovered in the available literature reports of 48 cases in the pediatric age group and have 5 additional cases of our own. From a careful review of the material, it would appear that certain aspects of the condition occur with sufficient frequency to merit consideration as a separate entity. According to Sandstrom (27), calcification of the intervertebral disks was first described by Luschka in 1858. Almost a half century later, it was demonstrated by Beneke (1897) in his Roentgen Study in the Cadaver. It was again described by Calve and Galland in 1922 (6). The calcification was believed by Schmorl (30), according to his classical study of this subject in 1932, to be the result of a degenerative process, without clinical significance. In the same year Rathcke (23) reported microscopically visible calcification in intervertebral disks at all ages. In 192...
52 citations
TL;DR: The author presents 4 cases in which spontaneous resorption of the herniated nuclear material and remission of symptoms occurred with conservative therapy alone, and suggests the need for neurosurgical intervention.
Abstract: Intervertebral-disk calcification in children is associated with pain, fever, leukocytosis, and an elevated erythrocyte sedimentation rate. It characteristically runs a benign course, with spontaneous resorption of the calcification and remission of symptoms. Herniation of the calcified nucleus pulposus is a rare complication, possibly producing minor symptoms and alarming roentgenographic findings which suggest the need for neurosurgical intervention. The author presents 4 cases in which spontaneous resorption of the herniated nuclear material and remission of symptoms occurred with conservative therapy alone.
47 citations
TL;DR: The number of dogs affected and number of calcified disks seemed to reach a steady level or a maximum at about 24 to 27 months of age, while Radiographic examination for calcified intervertebral disks in the dachshund is recommended at 24 to 30 years of age for heritability studies and selective breeding.
Abstract: Plain spinal radiography was performed in 40 dachshunds at regular intervals from 6 or 12 months of age to 2 years of age. A follow-up study at 3 to 4 years of age included 12 dogs. High incidence rates of intervertebral disk calcification were seen at 6 to 18 months of age. The number of dogs affected and number of calcified disks seemed to reach a steady level or a maximum at about 24 to 27 months of age. Dissolution of previously calcified disks without clinical signs was demonstrated, causing decreasing numbers of visibly calcified disks after 2 years of age. Radiographic examination for calcified intervertebral disks in the dachshund is recommended at 24 to 30 months of age for heritability studies and selective breeding.
40 citations
TL;DR: The different symptoms that correspond to intervertebral disk calcification are recalled and the decisions to be made in regard to radiological investigation and treatment are discussed.
Abstract: Intervertebral disk calcification is a rare childhood disease. The etiology of disk calcification in children remains unclear. We report three cases of children with cervical disk calcification. Their clinical manifestations are very different. The first patient mainly had a neurological deficiency. The second had neck pain and muscular deficit of the left musculus deltoideus. The third had isolated strong neck pain. By presenting these three cases, we want to recall the different symptoms that correspond to this disease and discuss the decisions to be made in regard to radiological investigation and treatment. Healing takes place spontaneously after several days, and the calcifications disappears after about 6 months after a stage of fragmentation. Conservative treatment by immobilization of the spine and analgesic therapy are sufficient. Operative treatment should be reserved for severe radicular pain or for significant and persistent sensorimotor deficits from either root or spinal cord compression.
34 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2021 | 1 |
| 2014 | 1 |
| 2012 | 3 |
| 2011 | 2 |
| 2009 | 1 |
| 2008 | 1 |