TL;DR: Exercise intensity was an important factor for reversing LV remodeling and improving aerobic capacity, endothelial function, and quality of life in patients with postinfarction heart failure.
Abstract: Background—Exercise training reduces the symptoms of chronic heart failure. Which exercise intensity yields maximal beneficial adaptations is controversial. Furthermore, the incidence of chronic heart failure increases with advanced age; it has been reported that 88% and 49% of patients with a first diagnosis of chronic heart failure are 65 and 80 years old, respectively. Despite this, most previous studies have excluded patients with an age 70 years. Our objective was to compare training programs with moderate versus high exercise intensity with regard to variables associated with cardiovascular function and prognosis in patients with postinfarction heart failure. Methods and Results—Twenty-seven patients with stable postinfarction heart failure who were undergoing optimal medical treatment, including -blockers and angiotensin-converting enzyme inhibitors (aged 75.511.1 years; left ventricular [LV] ejection fraction 29%; V u O2peak 13 mL · kg 1 · min 1 ) were randomized to either moderate continuous training (70% of highest measured heart rate, ie, peak heart rate) or aerobic interval training (95% of peak heart rate) 3 times per week for 12 weeks or to a control group that received standard advice regarding physical activity. V u O2peak increased more with aerobic interval training than moderate continuous training (46% versus 14%, P0.001) and was associated with reverse LV remodeling. LV end-diastolic and end-systolic volumes declined with aerobic interval training only, by 18% and 25%, respectively; LV ejection fraction increased 35%, and pro-brain natriuretic peptide decreased 40%. Improvement in brachial artery flow-mediated dilation (endothelial function) was greater with aerobic interval training, and mitochondrial function in lateral vastus muscle increased with aerobic interval training only. The MacNew global score for quality of life in cardiovascular disease increased in both exercise groups. No changes occurred in the control group. Conclusions—Exercise intensity was an important factor for reversing LV remodeling and improving aerobic capacity, endothelial function, and quality of life in patients with postinfarction heart failure. These findings may have important implications for exercise training in rehabilitation programs and future studies. (Circulation. 2007;115:3086-3094.)
TL;DR: Some of the mechanisms responsible for improved skeletal muscle metabolic control and changes in cardiovascular function in response to low‐ volume HIT are reviewed and insight is provided on the utility of low‐volume HIT for improving performance in athletes.
Abstract: Exercise training is a clinically proven, cost-effective, primary intervention that delays and in many cases prevents the health burdens associated with many chronic diseases. However, the precise type and dose of exercise needed to accrue health benefits is a contentious issue with no clear consensus recommendations for the prevention of inactivity-related disorders and chronic diseases. A growing body of evidence demonstrates that high-intensity interval training (HIT)canserveasaneffectivealternatetotraditionalendurance-basedtraining,inducingsimilar or even superior physiological adaptations in healthy individuals and diseased populations, at least when compared on a matched-work basis. While less well studied, low-volume HIT can also stimulate physiological remodelling comparable to moderate-intensity continuous training despite a substantially lower time commitment and reduced total exercise volume. Such findings areimportantgiventhat'lackoftime'remainsthemostcommonlycitedbarriertoregularexercise participation. Here we review some of the mechanisms responsible for improved skeletal muscle metabolic control and changes in cardiovascular function in response to low-volume HIT. We also consider the limited evidence regarding the potential application of HIT to people with, or at risk for, cardiometabolic disorders including type 2 diabetes. Finally, we provide insight on the utility of low-volume HIT for improving performance in athletes and highlight suggestions for future research.
TL;DR: High-aerobic intensity endurance interval training is significantly more effective than performing the same total work at either lactate threshold or at 70% HRmax, in improving VO2max.
Abstract: HELGERUD, J., K. HKYDAL, E. WANG, T. KARLSEN, P. BERG, M. BJERKAAS, T. SIMONSEN, C. HELGESEN, N. HJORTH, R. BACH, and J. HOFF. Aerobic High-Intensity Intervals Improve VO2max More Than Moderate Training. Med. Sci. Sports Exerc., Vol. 39, No. 4, pp. 665-671, 2007. Purpose: The present study compared the effects of aerobic endurance training at different intensities and with different methods matched for total work and frequency. Responses in maximal oxygen uptake (VO2max), stroke volume of the heart (SV), blood volume, lactate threshold (LT), and running economy (CR) were examined. Methods: Forty healthy, nonsmoking, moderately trained male subjects were randomly assigned to one of four groups:1) long slow distance (70% maximal heart rate; HRmax); 2) lactate threshold (85% HRmax); 3) 15/15 interval running (15 s of running at 90-95% HRmax followed by 15 s of active resting at 70% HRmax); and 4) 4 4 min of interval running (4 min of running at 90-95% HRmax followed by 3 min of active restingat 70% HRmax). All four training protocols resulted in similar total oxygen consumption and were performed 3 dIwk j1 for 8 wk. Results: High-intensity aerobic interval training resulted in significantly increased VO2max compared with long slow distanceandlactate-thresholdtrainingintensities(P G 0.01). The percentage increases for the 15/15 and 4 4 min groups were 5.5 and 7.2%, respectively, reflecting increases in VO2max from 60.5 to 64.4 mLIkg j1 Imin j1 and 55.5 to 60.4 mLIkg j1 Imin j1 . SV increased significantly by approximately 10% after interval training (P G 0.05). Conclusions: High-aerobic intensity endurance interval training is significantly more effective than performing the same total work at either lactate threshold or at 70% HRmax, in improving VO2max. The changes in VO2max correspond with changes in SV, indicating a close link between the two. Key Words: LACTATE THRESHOLD, AEROBIC POWER, 4 4-MIN INTERVALS, 15/15 TRAINING, STROKE VOLUME, BLOOD VOLUME
TL;DR: Given the markedly lower training volume in the SIT group, these data suggest that high‐intensity interval training is a time‐efficient strategy to increase skeletal muscle oxidative capacity and induce specific metabolic adaptations during exercise that are comparable to traditional ET.
Abstract: Low-volume ‘sprint’ interval training (SIT) stimulates rapid improvements in muscle oxidative capacity that are comparable to levels reached following traditional endurance training (ET) but no study has examined metabolic adaptations during exercise after these different training strategies. We hypothesized that SIT and ET would induce similar adaptations in markers of skeletal muscle carbohydrate (CHO) and lipid metabolism and metabolic control during exercise despite large differences in training volume and time commitment. Active but untrained subjects (23 ± 1 years) performed a constant-load cycling challenge (1 h at 65% of peak oxygen uptake ( ˙ VO2peak) before and after 6 weeks of either SIT or ET (n = 5 men and 5 women per group). SIT consisted of four to six repeats of a 30 s ‘all out’ Wingate Test (mean power output ∼500 W) with 4.5 min recovery between repeats, 3 days per week. ET consisted of 40‐60 min of continuous cycling at a workload that elicited ∼65% ˙ VO2peak (mean power output ∼150 W) per day, 5 days per week. Weekly time commitment (∼1.5 versus ∼4.5 h) and total training volume (∼225 versus ∼2250 kJ week −1 ) were substantially lower in SIT versus ET. Despite these differences, both protocols induced similar increases (P < 0.05) in mitochondrial markers for skeletal muscle CHO (pyruvate dehydrogenase E1α protein content) and lipid oxidation (3-hydroxyacyl CoA dehydrogenase maximal activity) and protein content of peroxisome proliferator-activated receptor-γ coactivator-1α. Glycogen and phosphocreatine utilization during exercise were reduced after training, and calculated rates of whole-body CHO and lipid oxidation were decreased and increased, respectively, with no differences between groups (all main effects, P < 0.05). Given the markedly lower training volume in the SIT group, these data suggest that high-intensity interval training is a time-efficient strategy to increase skeletal muscle oxidative capacity and induce specific metabolic adaptations during exercise that are comparable to traditional ET.
TL;DR: Enhanced aerobic endurance in soccer players improved soccer performance by increasing the distance covered, enhancing work intensity, and increasing the number of sprints and involvements with the ball during a match.
Abstract: HELGERUD, J., L. C. ENGEN, U. WISLOFF, and J. HOFF. Aerobic endurance training improves soccer performance.Med. Sci. Sports Exerc., Vol. 33, No. 11, 2001, pp. 1925–1931. Purpose: The aim of the present study was to study the effects of aerobic training on performance during soccer match and soccer specific tests. Methods: Nineteen male elite junior soccer players, age 18.1 0.8 yr, randomly assigned to the training group (N 9) and the control group (N 10) participated in the study. The specific aerobic training consisted of interval training, four times 4 min at 90 –95% of maximal heart rate, with a 3-min jog in between, twice per week for 8 wk. Players were monitored by video during two matches, one before and one after training. Results: In the training group: a) maximal oxygen uptake (V u O2max) increased from 58.1 4.5 mL·kg 1 ·min 1 to 64.3 3.9 mL·kg 1 ·min 1 (P 0.01); b) lactate threshold improved from 47.8 5.3 mL·kg 1 ·min 1 to 55.4 4.1 mL·kg 1 ·min 1 (P 0.01); c) running economy was also improved by 6.7% (P 0.05); d) distance covered during a match increased by 20% in the training group (P 0.01); e) number of sprints increased by 100% (P 0.01); f) number of involvements with the ball increased by 24% (P 0.05); g) the average work intensity during a soccer match, measured as percent of maximal heart rate, was enhanced from 82.7 3.4% to 85.6 3.1% (P 0.05); and h) no changes were found in maximal vertical jumping height, strength, speed, kicking velocity, kicking precision, or quality of passes after the training period. The control group showed no changes in any of the tested parameters. Conclusion: Enhanced aerobic endurance in soccer players improved soccer performance by increasing the distance covered, enhancing work intensity, and increasing the number of sprints and involvements with the ball during a match. Key Words: V u O2max, LACTATE THRESHOLD, RUNNING ECONOMY, SKILL