TL;DR: The usual approach to managing intertrigo is to minimize moisture and friction with absorptive powders such as cornstarch or with barrier creams, but patients should wear light, nonconstricting, and absorbent clothing and avoid wool and synthetic fibers.
Abstract: Intertrigo is inflammation of skinfolds caused by skin-on-skin friction. It is a common skin condition affecting opposing cutaneous or mucocutaneous surfaces. Intertrigo may present as diaper rash in children. The condition appears in natural and obesity-created body folds. The friction in these folds can lead to a variety of complications such as secondary bacterial or fungal infections. The usual approach to managing intertrigo is to minimize moisture and friction with absorptive powders such as cornstarch or with barrier creams. Patients should wear light, nonconstricting, and absorbent clothing and avoid wool and synthetic fibers. Physicians should educate patients about precautions with regard to heat, humidity, and outside activities. Physical exercise usually is desirable, but patients should shower afterward and dry intertriginous areas thoroughly. Wearing open-toed shoes can be beneficial for toe web intertrigo. Secondary bacterial and fungal infections should be treated with antiseptics, antibiotics, or antifungals, depending on the pathogens.
TL;DR: It is suggested that the initial change is nonunion of groups of connective tissue fibrils for elastic tissue, and the possibility is raised that local inflammation and topically applied corticosteroids may influence the production of striae.
Abstract: Five male patients with atrophic striae in the groins are reported. All patients received Mycolog cream*topically. None received corticosteroids orally or parenterally. No corticotropin was given. Current theories of the mechanism of the production of striae are discussed. We suggest that the initial change is nonunion of groups of connective tissue fibrils. This is most clearly demonstrated for elastic tissue. The possibility is raised that local inflammation and topically applied corticosteroids may influence the production of striae. The serious consequences of striae are mentioned. Caution is advised in the use of corticosteroids in the treatment of intertrigo.
TL;DR: In this paper, the authors evaluated the frequency of skin colonization by Fusarium spp. in high-risk hematologic patients and its impact on the subsequent development of invasive fusariosis.
TL;DR: 1. Structure, function and normal variation 2. Dermatological diagnosis 3. Pruritus 4. Pigmentary Change 5. Hair 6. Red patches and plaques 7. Intertrigo, balanitis and posthitis
Abstract: 1. Structure, function and normal variation 2. Dermatological diagnosis 3. Pruritus 4. Pigmentary Change 5. Hair 6. Red patches and plaques 7. Intertrigo, balanitis and posthitis 8. Erosions, ulcers, blisters 9. Palpable lesions - lumps and bumps 10. Pain and swelling
TL;DR: Medical treatment of candidal intertrigo usually requires topical administration of nystatin and azole group antifungals, and in case of predisposing immunosuppressive conditions or generalized infections, novel systemic agents with higher potency may be required.
Abstract: Intertrigo is a common inflammatory dermatosis of opposing skin surfaces that can be caused by a variety of infectious agents, most notably candida, under the effect of mechanical and environmental factors. Symptoms such as pain and itching significantly decrease quality of life, leading to high morbidity. A multitude of predisposing factors, particularly obesity, diabetes mellitus, and immunosuppressive conditions facilitate both the occurrence and recurrence of the disease. The diagnosis of candidal intertrigo is usually based on clinical appearance. However, a range of laboratory studies from simple tests to advanced methods can be carried out to confirm the diagnosis. Such tests are especially useful in treatment-resistant or recurrent cases for establishing a differential diagnosis. The first and key step of management is identification and correction of predisposing factors. Patients should be encouraged to lose weight, followed up properly after endocrinologic treatment and intestinal colonization or periorificial infections should be medically managed, especially in recurrent and resistant cases. Medical treatment of candidal intertrigo usually requires topical administration of nystatin and azole group antifungals. In this context, it is also possible to use magistral remedies safely and effectively. In case of predisposing immunosuppressive conditions or generalized infections, novel systemic agents with higher potency may be required.