Topic
Hypochromia
About: Hypochromia is a research topic. Over the lifetime, 108 publications have been published within this topic receiving 1683 citations.
Papers published on a yearly basis
Papers
TL;DR: The data summarized are compatible with the hypothesis that function of the loci of the β and δ chains of globin is wholly suppressed, quite possibly by a mutant "operator" gene affecting linked structural loci.
214 citations
TL;DR: The defect in Cooley’s anemia is not in total hemoglobin synthesis, but in the fabrications of circulating erythrocytes, which in turn have the associated manifestations of hypochromia, increased percentage of fetal hemoglobin and shortened survival time.
128 citations
TL;DR: Evaluated hematological changes in samples of blood obtained from 248 dogs naturally infected with large Babesia found thrombocytopenia was detected in 99.5% of dogs, but only 15% of examined animals showed increase of MPV, which suggests a response of the bone marrow.
89 citations
TL;DR: The usefulness of hypochromia and microcytosis as indicators of iron deficiency was examined in 365 geriatric patients aged 67-96 years and fifteen per cent of the 201 iron deficient subjects were also shown to have coexisting vitamin B12 deficiency.
Abstract: The usefulness of hypochromia (MCH or = 80 (fl) vs. counterparts with MCV or = 26 pg). Fifteen per cent of the 201 iron deficient subjects were also shown to have coexisting vitamin B12 deficiency. There was a comparable (16%) prevalence of this haematinic deficiency in the subgroup of 31 iron deficient patients with MCH or = 80 fl.
86 citations
TL;DR: A chronic disturbance of erythropoiesis which is marked by microcytosis and hypochromia and by the production of red corpuscles of bizarre shape and red cells resembling targets is represented.
Abstract: We are prompted to make this report because the cases to be described seem to represent a disorder of the blood in adolescents and adults which has hitherto received little attention. It is a chronic disturbance of erythropoiesis which is marked by microcytosis and hypochromia and by the production of red corpuscles of bizarre shape and red cells resembling targets. Normoblasts, polychromatophilic and particularly stippled red cells are found in the circulating blood. These abnormalities occur in spite of the presence of little or no anemia and even in the face of an actual increase in the red cell count above normal. The red corpuscles possess an unusually great resistance to destruction in hypotonic solutions of sodium chloride, yet there may be some evidence of increased red cell destruction in vivo. The patients may have no complaints, but splenomegaly is often found and roentgenographically demonstrable changes in the bones may
64 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2021 | 2 |
| 2020 | 2 |
| 2019 | 5 |
| 2018 | 1 |
| 2017 | 4 |
| 2016 | 2 |