Topic
Hyperpnea
About: Hyperpnea is a research topic. Over the lifetime, 663 publications have been published within this topic receiving 22161 citations. The topic is also known as: forced respiration & forced ventilation.
Papers published on a yearly basis
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Papers
TL;DR: In this paper, the authors investigated a child with profound psychomotor retardation who had had an occipital meningoencephalocele removed at birth and showed a large midline defect in the posterior fossa and absence of the vermis.
Abstract: SOME TWO YEARS AGO we investigated a child with profound psychomotor retardation who had had an occipital meningoencephalocele removed at birth. Contrast studies were carried out which showed a large midline defect in the posterior fossa and absence of the vermis. At the time we disregarded the nurses’ comments about the child’s abnormal breathing. A year later, Dr. P. P. Demers referred this patient’s baby brother to us because he was concerned about his abnormal breathing and xetarded development. It was then found that a third and older child in this family was Tetarded, ataxic, and breathing abnormally. Finally we were able to trace yet another sibling who had died in fancy and who, at autopsy, proved to have agenesis of the vermis. This .diagnosis was then confirmed in the two affected living children by contrast studies. From this investigation there emerged a familial syndrome of episodic hyperpnea, abnormal eye movements, ataxia, and mental retardation associated with a common malformation in the four affected siblings, agenesis of the vermis. This syndrome has not previously been described in the literature. The affected children will be presented in the order in which the abnormality was identified, which happens to be in reverse to the birth order (Fig. 1).
625 citations
TL;DR: The O2 cost of exercise hyperpnea is a significant fraction of the total VO2max but is not sufficient to cause a critical level of "useful"hyperpnea to be achieved in healthy subjects.
Abstract: We addressed two questions concerned with the metabolic cost and performance of respiratory muscles in healthy young subjects during exercise: 1) does exercise hyperpnea ever attain a “critical use...
405 citations
TL;DR: It is concluded that during maximal exercise, highly trained individuals often reach the mechanical limits of the lung and respiratory muscle for producing alveolar ventilation, which is achieved at a considerable metabolic cost but with a mechanically optimal pattern of breathing and respiratory Muscle recruitment and without sacrifice of a significantAlveolar hyperventilation.
Abstract: We determined how close highly trained athletes [n = 8; maximal oxygen consumption (VO2max) = 73 +/- 1 mlkg-1min-1] came to their mechanical limits for generating expiratory airflow and inspirato
400 citations
TL;DR: From this investigation there emerged a familial syndrome of episodic hyperpnea, abnormal eye movements, ataxia, and mental retardation associated with a common malformation in the four affected siblings, agenesis of the vermis.
Abstract: regarded the nurses’ comments about the child’s abnormal breathing. A year later, Dr P P Demers referred this patient’s baby brother to us because he was concerned about his abnormal breathing and retarded development. It was then found that a third and older child in this family was retarded, ataxic, and breathing abnormally. Finally we were able to trace yet another sibling who had died in infancy and who, at autopsy, proved to have agenesis of the vermis. This diagnosis was then confirmed in the two affected living children by contrast studies. From this investigation there emerged a familial syndrome of episodic hyperpnea, abnormal eye movements, ataxia, and mental retardation associated with a common malformation in the four affected siblings, agenesis of the vermis. This syndrome has not previously been described in the literature.
309 citations
TL;DR: The studies indicate that ventilation with the subject breathing air during rest and steady-state exercise is not affected by the operation, the carotid bodies appear to be responsible for the hyperpnea of hypoxia, and this response is not enhanced by moderate exercise, and the ventilatory response to increased arterial carbon dioxide tension is reduced after bilateralcarotid-body resection.
Abstract: To investigate the role of the carotid bodies in the control of ventilation during rest and moderate exercise, seven asthmatic subjects who had undergone bilateral carotid-body resection (the barostatic reflexes remained intact) were studied while they were breathing air and hypoxic, hypercapnic, and hyperoxic gas. During breathing of air and 25 per cent oxygen, ventilation was not different between this group and control subjects either at rest or during exercise. The hyperpnea of hypoxia was absent, and the ventilatory response to increased arterial carbon dioxide tension was reduced 30 per cent after carotid-body resection. These studies indicate that ventilation with the subject breathing air during rest and steady-state exercise is not affected by the operation, the carotid bodies appear to be responsible for the hyperpnea of hypoxia, and this response is not enhanced by moderate exercise, and the ventilatory response to increased arterial carbon dioxide tension is reduced after bilateral ca...
294 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2025 | 4 |
| 2024 | 4 |
| 2023 | 9 |
| 2022 | 16 |
| 2021 | 5 |
| 2020 | 8 |