TL;DR: The experimental data demonstrate that amentoflavone, in contrast to hypericin, presents a very active compound with regard to the inhibition of [3H]-flumazenil binding in vitro and thus might be involved in the antidepressant effects of Hypericum perforatum extracts.
TL;DR: The main conclusion from the above data is that genetic and environmental factors both play a role in determining the composition of essential oils of the Hypericum species studied.
TL;DR: The essential oil of Hypericum olympicum L. was analysed for the first time and was compared to the essential oil H. perforatum L. from the same location.
TL;DR: The composition of the essential oils of the Hypericum perforatum L, Hypericum tetrapterum Fries and Hypericum olympicum L is reported in this paper.
Abstract: The composition of the essential oils of the Hypericum perforatum L., Hypericum tetrapterum Fries and Hypericum olympicum L. is reported. GC-MS analyses showed α-pinene (21.0%) and 2-methyl-octane (12.6%) as the most abundant components of H. perforatum, whilst α-copaene (11.3%) and α-longipinene (9.7%) were the major constituents of H. tetrapterum; those of H. olympicum oil were germacrene D (16.0%) and ( £ ')-caryophyllene (7.4%).
TL;DR: Experimental studies have proven the traditional use of Hypericum olympicum in inflamed skin problems acting by inhibition of the inflammatory pathway and recovery of DNA damage induced experimentally.