Topic
Hexol
About: Hexol is a research topic. Over the lifetime, 37 publications have been published within this topic receiving 387 citations.
Papers
TL;DR: In this paper, the authors report methods for the synthesis of all twelve possible O-me-thylation products from 5,11,17,23,29,35-hexa-tert-butylcalix-37,38,39,40,41,42-hexol.
Abstract: We here report methods for the synthesis of all twelve possible O-me- thylation products from 5,11,17,23,29;35-hexa-tert-butylcalix[6]arene- 37,38,39,40,41,42-hexol (1): one mono-, three di-, three tri-, three tetra-, one penta-, and one hexamethylated product. The strategies used are (i) direct O-methylation with different (1)/K 2 CO 3 ratios, (ii) selective mono-O-methylation of O-alkylation products, (iii) demethyla- tion with TiCl 4 or LiI, and (iv) protection-deprotection with a benzyl group or an o- or m-xylenyl group. We believe that these O-methylation products are useful as basic skeletons to design functionalized calix- [6] arenes with the desired number of substituents and regioselectively- positioned functional groups
58 citations
TL;DR: The photooxygenation of trans-8-(acetyloxy)bicyclo[4.2.0]octa-2,4-dien-7-yl acetate afforded the bicyclic endoperoxide.
42 citations
TL;DR: In this paper, the validity of the theories of Derjaguin-LandauVerwey-Overbeek, of Whetham and of Tezak in relation to these coagulation data has been discussed.
Abstract: ABS>Sols whose charge had been reversed by 9-tungstophosphoric acid were coagulated by simple mono-, di-, triand tetravalent cations. These sols, which were originally positively charged, behaved as normal negative sols to the above coagulating cations. The influence upon the coagulation concentration of a number of procedures for preparing the recharged sols was investigated. The coagulation concentration of a hexol for negative silver halide sols has been determined at several pH values. At low pH, the hexol exhibits a coagulation concentration consistent with ionization to a hexavalent species. Just as had been found previously for highly charged anions, the highly charged hexol cation causes reversal of charge on the colloidal particles. The availability of critical coagulation concentrations of highly charged ions has made possible a detailed comparison of coagulation data with the requirements of existing quantitative expressions for the Schulze-Hardy rule. The validity of the theories of Derjaguin-LandauVerwey-Overbeek, of Whetham and of Tezak in relation to these coagulation data has been discussed. (auth)
39 citations
TL;DR: The distribution of carrier-free 48V between methyl isobutyl carbinol (hexol) and 0·5 M (H,NaClO4) has been measured radiometrically at 25°C as a function of −log [H+].
36 citations
TL;DR: Asymmetric synthesis of the 18-membered lichen macrolide (+)-aspicilin has been achieved in 14 steps and 11% overall yield, starting from an achiral hydrocarbon, (3E)-hexadeca-1,3,15-triene as discussed by the authors.
Abstract: Asymmetric synthesis of the 18-membered lichen macrolide (+)-aspicilin has been achieved in 14 steps and 11% overall yield, starting from an achiral hydrocarbon, (3E)-hexadeca-1,3,15-triene. All four stereogenic carbinol centers have been introduced by three Sharpless asymmetric dihydroxylation (AD) reactions, using both AD-mix-β and AD-mix-α to produce the hexol with very high regio- and enantioselectivity (epimeric excess of 88% at position 2,96% at positions 3 and 4, and 86% at position 15)
33 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2020 | 1 |
| 2019 | 1 |
| 2018 | 1 |
| 2017 | 2 |
| 2011 | 1 |
| 2009 | 1 |