Topic
Hemoglobin, alpha 2
About: Hemoglobin, alpha 2 is a research topic. Over the lifetime, 4 publications have been published within this topic receiving 69 citations. The topic is also known as: HBA1 & truncated HbA2.
Papers
TL;DR: Differences in interface stability provide a structural explanation for the published observation that the alpha 2 beta 2 tetramer assembles via a stable alpha 1 beta 1 dimer intermediate, whereas assembly of the CO beta 4 tetramer is characterized more accurately by a monomer-tetramer equilibrium.
46 citations
TL;DR: In this article, the relative role of various chloride binding sites in determining the oxygen affinity of hemoglobin using abnormal hemoglobins such as Hb York (Hb Y) (alpha 2 beta 2(146)Pro), Hb Malmo(Hb M), and Hb S was estimated.
6 citations
TL;DR: It was seen that the distribution of allele frequencies and that of genotypes were not statistically significant between carrier and control samples, and an A/G polymorphism in the downstream untranslated region (+861 G>A) of the HBA2 gene was observed, the first report in Turkish population.
4 citations
TL;DR: The double-mixing HPLC results suggested that in the second step of ligation alpha chains reacted faster than the beta chains, and the main diliganded species formed was alpha I beta ICO (alpha IICO beta II) or its isomer alpha ICO I(alpha II beta IICO).
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2011 | 1 |
| 1994 | 1 |
| 1991 | 1 |
| 1983 | 1 |