TL;DR: The Chinese hamster first played a role in infectious disease research to type pneumococci strains and was subsequently used in a variety of infectious disease and epidemiological studies, becoming a useful tool for characterizing the metabolic disorder and developing therapies for the human disease.
Abstract: Publisher Summary Chinese hamsters are small rodents with a grayish black coat and a black dorsal stripe. Adult animals weigh approximately 39–46 gm, and measure approximately 9 cm in length. This species has been shown to be susceptible to a number of experimentally induced viral, bacterial, and parasitic infections. In recent years, the Chinese hamster's contributions as a laboratory animal have been largely overshadowed by the focus on its cell lines and the role it plays in scientific research and biotechnology. The Chinese hamster used in biomedical research is traditionally classified as Cricetulus griseus. It has several biological features that have helped promote its use in biomedical research and these attributes include its small size, polyestrous cycle, short gestation period, and low chromosome number. The Chinese hamster has a low incidence of spontaneous and endogenous viral infections. This species has been shown to be susceptible to a number of experimentally induced viral, bacterial, and parasitic infections. Chinese hamster-derived cells have played a major role in cytogenetic toxicity assays and the production of glycosylated therapeutic proteins. The behavior, research uses, and general toxicology of the Chinese hamster are summarized in this chapter.
TL;DR: The results of phylogenetic and network analyses indicated that there was a deep separation among the distinct lineages within the genus Cricetulus, and the Anatolian population ofgray hamster may have hosted a source population of the gray hamster for expansion to adjacent regions in the past period.
Abstract: Although genetic diversity and phylogenetic status of the gray hamster (Cricetulus migratorius) have been investigated from different regions in previous studies, genetic data on this species from ...
TL;DR: The data obtained agree with the hypothesis of Matthey (1961) claiming that the paired parts of X and Y chromosomes of the species with large Y chromosome and visible chiasma have autosomal origin, Therefore, X andY chromosomes of Cricetulus migratorius could be originated via autosome-gonosome translocation.
Abstract: The sequence of X and Y chromosomes pairing at meiotic prophase in the Armenian hamster Cricetulus migratorius Pall., 1770 gas been studied. The results of differential staining (C-, Ag-NOR) of mitotic chromosomes are presented. The rare case of interstitial synapsis of the sex chromosomes has been described. Earlier it was established only for Peromyscus sitkensis (Hale, Greenbaum, 1986). Pairing of the X and Y chromosomes is initiated at an interstitial position of the euchromatic region with subsequent synapsis towards the telomeres of the short arms. The latter conjugate completely and in this state do not differ outwardly from autosomal bivalents. The long arms remain asynaptic (heteropycnotic) constantly but at the meiosis undergo different morphological changes (thickness, bulging, clear showing filament structures, etc.) The data obtained agree with the hypothesis of Matthey (1961) claiming that the paired parts of X and Y chromosomes of the species with large Y chromosome and visible chiasma have autosomal origin. Therefore, X and Y chromosomes of Cricetulus migratorius could be originated via autosome-gonosome translocation.
TL;DR: The yellow-bellied mouse and gray hamster were found at all stations, whereas the forest dormouse and social vole were more selective in their choice of stations, as a result, the width of the spatial niches for theyellow-bellies mouse andgray hamster is greater than that of the forest roommouse andsocial vole.
Abstract: The features of the spatial distribution of four species of Mouse-Like rodents (Sylvaemus fulvipectus, Cricetulus migratorius, Microtus socialis, and Dryomys nitedula) in the forest associations of the foothill zone of the Republic of Dagestan are analyzed. Sixteen environmental parameters are selected, of which ten significantly showed interspecific differences. The distribution of rodent species is demonstrated relative to the environmental characteristics taken into account in the descriptions; the preferences and requirements for the environment of each species are revealed. Thus, the yellow-bellied mouse and gray hamster were found at all stations, whereas the forest dormouse and social vole were more selective in their choice of stations. As a result, the width of the spatial niches for the yellow-bellied mouse and gray hamster is greater than that of the forest dormouse and social vole. The results of pairwise comparison of the spatial niches of studied rodent species reveal low values of their overlap.
TL;DR: In this paper, the relative fatness of gray hamsters was analyzed statistically with respect to the variations at all seasons and among years of the relative Fatness in gray hamster during 1968-1983.
Abstract: The authors in this paper have analysed statistically with respect to the variations at all seasons and among years of the relative fatness in gray hamster during 1968-1983. It was compared with house mouse(Mus muscu-lus L.)in the same region.
The relative fatness of each animal was calculated by the following formula.
where K stands for the relative fatness,W the weight in grams,L the length of head and body in cms.
Sexual difference with respect to fatness was observed, the female adults were fatter than the male adults.
There were seasonal variations with respect to the relative fatness.The materials from the years 1972-1983 indicated the fatness of the gray hamst-er(K) was highest in autumn(October)and lowest during the summer (June to August),but from early winter(November)till next spring(April)the fatness was stable.
The variations among years of the relative fatness in male adults showed that it had an obvious difference,but no correlation to its population density.
The materials in October during 1968-1983 indicated that the fatness in gray hamster had very obvious correlation with the numbers of dominant species,house mouse(Mits musculus L.)in Taxihe,Manas county,Xinjiang Uy-gur Autonomous Region,the correlation coefficient r=-0.8212.