TL;DR: The purpose of this paper is to report what is considered to be the first recognized case of perihepatitis as it pertains to females.
Abstract: THE clinical manifestations of gonococcal infection may take many forms, the most commonly recognized being the urogenital. Extragenital spread or localization can result in gonococcemia with cutaneous manifestations, meningitis, endocarditis, pericarditis, arthritis, tenosynovitis, perihepatitis, parotitis and proctitis.1 2 3 Perihepatitis was first described by Stajano4 in 1919. Curtis,5 in 1930, and Fitz-Hugh, in 19346 and 1936,7 reported on this syndrome, which now bears their names. Reports by Stanley8 (1946) and Vickers and Maloney (1964)9 further defined and described the syndrome as it pertains to females. The purpose of this paper is to report what is considered to be the first recognized case . . .
TL;DR: The purpose of this communication is to record the experience with cutaneous gonococcosis at a general charity hospital and to re-emphasize the diagnostic value of this type of eruption, particularly when the primary infection is not clinically evident or demonstrable.
Abstract: The specificity of the cutaneous lesions in gonococcemia has received little or no attention in textbooks of dermatology and internal medicine. Moreover, the English medical literature of the past 20 years contains no report dealing with the characteristic hemorrhagic vesiculopustular exanthem in this disease. Therefore, the purpose of this communication is to record the experience with cutaneous gonococcosis at a general charity hospital and to re-emphasize the diagnostic value of this type of eruption, particularly when the primary infection is not clinically evident or demonstrable. Clinical Material The 14 cases of this survey constitute the largest series reported to date of patients with gonococcal skin lesions. The patients were encountered at the Jefferson Davis Hospital during the period extending from January, 1957, to April, 1963. The sole criterion for the selection of cases was the presence of a characteristic cutaneous eruption. The suporting evidence for the diagnosis of gonococcal disease
TL;DR: In this paper, the authors found that an increasing proportion of patients seen with such complaints at the University of Washington Hospitals, Seattle, have had systemic meningococcal infection rather than DGI.
Abstract: • Sexually active young adults with an acute arthralgia or arthritis, with or without associated skin lesions, often have disseminated gonococcal infection (DGI). In recent years, an increasing proportion of patients seen with such complaints at the University of Washington Hospitals, Seattle, have had systemic meningococcal infection rather than DGI. Among 151 patients with acute arthritis studied prospectively from 1970 to 1972, blood or synovial fluid cultures yielded Neisseria gonorrhoeae in 30 patients and Neisseria meningitidis in two. Among 62 patients meeting the same criteria who were studied prospectively from 1980 to 1983, blood or synovial fluid cultures yielded gonococci in nine and meningococci in five. Separate analysis of blood culture results from two University of Washington Hospitals also revealed a decline in the number of cases of gonococcemia from 1970 through 1984 and a shift in the relative numbers of patients with bacteremia due to N gonorrhoeae and N meningitidis . The observed decline in gonococcemia coincides with a decline in the proportion of gonorrhea in Seattle caused by gonococcal strains that have been associated with DGI. ( Arch Intern Med 1987;147:281-283)
TL;DR: A case of gonococcemia in a female patient with fever, arthritis, and characteristic cutaneous manifestations is presented, and similar findings were noted in the patient's husband, and Neisseria gonorrhoeae was cultured from both partners.
Abstract: A case of gonococcemia in a female patient with fever, arthritis, and characteristic cutaneous manifestations is presented. Similar findings were noted in the patient's husband, and Neisseria gonorrhoeae was cultured from both partners. Gram-negative diplococci were seen in histopathologic sections of a typical skin lesion. The subject of cutaneous manifestations of gonococcemia is reviewed.
TL;DR: This patient with primary idiopathic cutaneous pustular vasculitis had evidence of both circulating immune complexes and serum enhancement of neutrophil migration, and extensive evaluation failed to reveal any underlying systemic disease.
Abstract: Pustular cutaneous vasculitis results from a heterogeneous group of disorders characterized by pustules on purpuric bases. Although the cause of this group of conditions is diverse, the histopathologic picture of the lesions is the same, showing a Sweet's-like or leukocytoclastic vasculitis. These distinctive lesions may occur in patients with Behcet's syndrome, bowel-associated dermatosis-arthritis syndrome, or chronic gonococcemia. We describe, for the first time, a patient with primary idiopathic cutaneous pustular vasculitis. This patient had evidence of both circulating immune complexes and serum enhancement of neutrophil migration. Extensive evaluation failed to reveal any underlying systemic disease. A classification of the pustular vasculitides is proposed.