Topic
Gene-for-gene relationship
About: Gene-for-gene relationship is a research topic. Over the lifetime, 88 publications have been published within this topic receiving 18056 citations.
Papers published on a yearly basis
Papers
TL;DR: The gene-for-gene hypothesis suggests that for each gene that conditions reaction in the host there is a correspond ing gene in the parasite that conditions pathogenicity.
Abstract: One of the most successful means of controlling plant diseases has been the development of varieties with major or vertical resistance genes. This type of resistance is easily manipulated in a breeding program and is efIec tive until strains of the pathogen to which it does not confer resistance be come established. Then, if another gene that conditions resistance to the new strains of the pathogen is available, this resistance gene may be incorporated into the variety by the plant breeder. In doing this, the breeder either con sciously or unconsciously is applying the principle of the gene-far-gene hypothesis. Plants resistant to races that are virulent on old varieties possess the new resistance gene. With the diseases of some crops, this process has becn repeated at relatively frequent intervals (4D, 42, 82). However, in some instances a single gene has conferred adequate resistance for many years 80,82). In plant diseases caused by living organisms, the same phenomena: in fection type in rusts, percent of infected plants in smuts of cereals, fleck or lesion in apple scab, are criteria of both the reaction of the host and the pathogenicity of the parasite. They indicate the relative resistance or sus ceptibility of the host and the relative avirulence or virulence of the para site. The gene-for-gene hypothesis was proposed (20,25) as the simplest ex planation of the results of studies on the inheritance of pathogenicity in the .flax rust fungus, M elampsora lini. On varieties of flax, Linum usitatissimum that have one gene for resistance to the avirulent parent race, F 2 cultures of the fungus segregate into monofactorial ratios. On varieties having 2, 3, or 4 genes for resistance to the avirulent parent race, the F2 cultures segregate into bi-, trio, or tetra factorial ratios (20-22) respectively. This suggests that for each gene that conditions reaction in the host there is a correspond ing gene in the parasite that conditions pathogenicity. Each gene in either member of a host-parasite system may be identified only by its counterpart in the other member of the system.
3,362 citations
TL;DR: A yeast artificial chromosome clone that spans the Pto region was identified and used to probe a leaf complementary DNA (cDNA) library, suggesting a role for Pto in a signal transduction pathway.
Abstract: The Pto gene in tomato confers resistance to races of Pseudomonas syringae pv. tomato that carry the avirulence gene avrPto. A yeast artificial chromosome clone that spans the Pto region was identified and used to probe a leaf complementary DNA (cDNA) library. A cDNA clone was isolated that represents a gene family, at least six members of which genetically cosegregate with Pto. When susceptible tomato plants were transformed with a cDNA from this family, they were resistant to the pathogen. Analysis of the amino acid sequence revealed similarity to serine-threonine protein kinases, suggesting a role for Pto in a signal transduction pathway.
1,543 citations
TL;DR: The sequence similarity of N, Toll, and IL-1R suggests that N mediates rapid gene induction and TMV resistance through a Toll-IL-1-like pathway.
1,399 citations
TL;DR: It is reported here that transient expression of AVR‐Pita176 inside plant cells results in a Pi‐ta‐dependent resistance response, and data suggest that the AVR-Pita 176 protein binds directly to the Pi‐TA LRD region inside the plant cell to initiate a Pi-ta‐mediated defense response.
Abstract: Rice expressing the Pi-ta gene is resistant to strains of the rice blast fungus, Magnaporthe grisea, expressing AVR-Pita in a gene-for-gene relationship. Pi-ta encodes a putative cytoplasmic receptor with a centrally localized nucleotide-binding site and leucine-rich domain (LRD) at the C-terminus. AVR-Pita is predicted to encode a metalloprotease with an N-terminal secretory signal and pro-protein sequences. AVR-Pita(176) lacks the secretory and pro-protein sequences. We report here that transient expression of AVR-Pita(176) inside plant cells results in a Pi-ta-dependent resistance response. AVR-Pita(176) protein is shown to bind specifically to the LRD of the Pi-ta protein, both in the yeast two-hybrid system and in an in vitro binding assay. Single amino acid substitutions in the Pi-ta LRD or in the AVR-Pita(176) protease motif that result in loss of resistance in the plant also disrupt the physical interaction, both in yeast and in vitro. These data suggest that the AVR-Pita(176) protein binds directly to the Pi-ta LRD region inside the plant cell to initiate a Pi-ta-mediated defense response.
1,275 citations
TL;DR: Publisher Summary The type of pustule developed on a host variety following inoculation with a race of rust is the criterion both of the reaction of that variety to the race and of the pathogenicity of that race to the variety.
Abstract: Publisher Summary The type of pustule developed on a host variety following inoculation with a race of rust is the criterion both of the reaction of that variety to the race and of the pathogenicity of that race to the variety. Races of rust—genes for pathogenicity—are identified by the reaction of a series of varieties termed “rust differentials.” Genes for rust reaction are identified by the pathogenicity of races of rust. Rust resistance in flax is inherited as a dominant character although with some genes, dominance is not complete. Virulence in flax rust, melampsora lini, with one exception, is inherited as a recessive character. F 2 cultures of hybrids among races of flax rust segregated for pathogenicity on the differential varieties in accordance with the number of genes in the differential that conditioned resistance to the avirulent parent race.
1,234 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2021 | 1 |
| 2020 | 1 |
| 2019 | 1 |
| 2018 | 1 |
| 2016 | 1 |
| 2015 | 1 |