TL;DR: Insight into FtsQBL complex formation will facilitate drug design and make it an attractive target for protein-protein interaction inhibitors intended to block bacterial cell division.
TL;DR: In vivo site-specific photo cross-linking was used to probe the surface of the FtsQ periplasmic domain for its interaction interfaces with FtsB and FtsL, and an interaction hot spot was identified around residue Ser-250 in the C-terminal region of FTSQ.