Enantioselective intermolecular alkene arylamination was achieved via gold redox catalysis. Screening of ligands revealed chiral P,N-ligands as the optimal choice, giving alkene aminoarylation with good yields (up to 80%) and excellent stereoselectivity (up to 99:1 er). As the first example of enantioselective gold redox catalysis, this work confirmed the feasibility of applying a chiral ligand at the gold(I) stage with stereodetermining step (SDS) at gold(III) intermediate, opening new direction to conduct gold redox catalysis with stereochemistry control.
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