About: Fish bone is a research topic. Over the lifetime, 893 publications have been published within this topic receiving 7093 citations. The topic is also known as: fishbone.
TL;DR: Bone deformities associated with nutrient deficiencies and toxicities in various fish can provide an excellent model to study gene action, cell differentiation, morphogenesis, species differences in phenotypic expression of genetic abnormalities, deposition of calcium, phosphorus and other trace elements in cartilage and skeletal tissues in response to vitamins and hormones and nutrient interactions.
TL;DR: In this paper, a biphasic material was found: biological hydroxyapatite/beta-TCP in a 87/13 ratio in a vitro cytotoxicity test assessed that all materials are non-cytotoxic.
TL;DR: In general fatty fish species showed higher lipid levels in the bones compared to lean fish species, and Saithe and salmon were found to be significantly different in the levels of lipid, protein and ash, and ash/protein ratio in the fish bones.
Abstract: The chemical composition, content of minerals and the profiles of amino acids and fatty acids were analyzed in fish bones from eight different species of fish. Fish bones varied significantly in chemical composition. The main difference was lipid content ranging from 23 g/kg in cod (Gadus morhua) to 509 g/kg in mackerel (Scomber scombrus). In general fatty fish species showed higher lipid levels in the bones compared to lean fish species. Similarly, lower levels of protein and ash were observed in bones from fatty fish species. Protein levels differed from 363 g/kg lipid free dry matter (dm) to 568 g/kg lipid free dm with a concomitant inverse difference in ash content. Ash to protein ratio differed from 0.78 to 1.71 with the lowest level in fish that naturally have highest swimming and physical activity. Saithe (Pollachius virens) and salmon (Salmo salar) were found to be significantly different in the levels of lipid, protein and ash, and ash/protein ratio in the bones. Only small differences were observed in the level of amino acids although species specific differences were observed. The levels of Ca and P in lipid free fish bones were about the same in all species analyzed. Fatty acid profile differed in relation to total lipid levels in the fish bones, but some minor differences between fish species were observed.
TL;DR: It is believed that a combination of oral examination followed by flexible endoscopy is indicated in all patients because of the serious potential complication from fish bone ingestion, and when triangular bones in the hypopharynx are encountered, rigid laryngoesophagoscopy should be considered.
Abstract: A prospective study was performed on 358 patients to examine the diagnosis, management, and natural history of fish bone ingestion. All patients admitted with the complaint had a thorough oral examination. Flexible endoscopy under local pharyngeal anesthesia would be performed on patients with negative findings. Of 117 fish bones encountered, 103 were removed (direct removal, 21; endoscopic removal, 82) and 12 were inadvertently dislodged. One was missed and the other one necessitated removal with rigid laryngoesophagoscopy under general anesthesia. Morbidity (1%) occurred in patients with triangular bones in the hypopharynx, resulting in one mucosal tear and two lengthy procedures. Mean hospital stay was 7 hours. Prediction of the presence of fish bones by symptoms and radiograph was poor. The location of symptoms, however, was useful in guiding the endoscopist to the site of lodgment. Of patients who refused endoscopy, only one (2.8%) developed retropharyngeal abscess. As compared to those who received endoscopy, 31.8% had fish bones detected. As the yield of fish bone detected was also inversely related to the duration of symptoms, we strongly suspect that most of the unremoved fish bones would be dislodged and passed. However, because of the serious potential complication from fish bone ingestion, we believe that a combination of oral examination followed by flexible endoscopy is indicated in all patients. When triangular bones in the hypopharynx are encountered, rigid laryngoesophagoscopy should be considered. This protocol had safely and effectively dealt with the present series of patients.
TL;DR: Clinical presentation and radiography are unreliable in the preoperative diagnosis of fish bone perforation of the GI tract, but this limitation can be overcome with the use of CT, which is accurate in showing the offending fish bone.
Abstract: OBJECTIVE. Foreign body perforation of the gastrointestinal (GI) tract has diverse clinical manifestations, and the correct preoperative diagnosis is seldom made. We report our experience with the use of CT in the preoperative diagnosis of fish bone perforation of the GI tract in seven patients. To our knowledge, this series is the largest to date addressing the role of CT in the diagnosis of fish bone perforation.CONCLUSION. Clinical presentation and radiography are unreliable in the preoperative diagnosis of fish bone perforation of the GI tract. This limitation can be overcome with the use of CT, which is accurate in showing the offending fish bone. The accuracy of CT is limited by observer dependence. A high index of suspicion should always be maintained for the correct diagnosis to be made.