Topic
Filaricides
About: Filaricides is a research topic. Over the lifetime, 42 publications have been published within this topic receiving 181 citations.
Papers
39 citations
TL;DR: 1,3,8-Triazabicyclo[4.4.0]decan-2-ones and -thiones varying substituents at positions 3 and 8 have been synthesized and some of the compounds showed moderate microfilaricidal activity in cotton rats.
Abstract: 1,3,8-Triazabicyclo[4.4.0]decan-2-ones and -thiones varying substituents at positions 3 and 8 have been synthesized. When tested in cotton rats for their antifilarial activity against Litomosoides carinii, some of the compounds showed moderate microfilaricidal activity.
19 citations
TL;DR: The synthesis of 3-ethyl-8-methyl-1,3,8-triazabicyclo[4,4,0]decan-2-one possessing high microfilaricidal activity is reported.
Abstract: The synthesis of 3-ethyl-8-methyl-1,3,8-triazabicyclo[4,4,0]decan-2-one possessing high microfilaricidal activity is reported.
17 citations
Journal Article•
11 citations
11 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2018 | 1 |
| 2017 | 1 |
| 2015 | 1 |
| 2011 | 1 |
| 2008 | 1 |
| 2006 | 1 |