TL;DR: The present report describes the successful treatment of cerebral symptomatic vasospasm after subarachnoid hemorrhage (SAH) with super-selective intra-arterial infusion of fasudil hydrochloride (ERIL®), which led to early improvement in neurological function after the procedure.
Abstract: The present report describes the successful treatment of cerebral symptomatic vasospasm (SVS) after subarachnoid hemorrhage (SAH) with super-selective intra-arterial infusion of fasudil hydrochloride (ERIL((R))). We treated seventeen vascular territories in 12 patients with selective intra-arterial infusion of fasudil hydrochloride (FSD). FSD was infused through a catheter (a microcatheter in nine patients) at a rate of 1.0 to 1.5 mg/minute (total dose=30 to 60mg/1 vessel) for each vascular territory. Nineteen vascular territories (100%) were angiographically dilated and seven patients (58%) showed early improvement in neurological function after the procedure.
TL;DR: In this paper, the authors discuss the evaluation of structural and masculine characteristics of scientific medicine, consideration of other problems caused by gendered structure of medicine and potentials that can be provided by female point of view in the actualization of humanistic medical practice.
Abstract: As an applied science it is known that medicine has a masculine point of view, operation structure and discourse in within historical process; and these masculine characteristics have been performed in a wide range from spiritual practices to traditional folk medicine; from temple medicine to clinic practices based on scientific – experimental methods. Historical process is the witness of transformation from therapeutic “wise” women of ancient cultures and “physician” queens to “witch” hunts of Middle Age and seductive “blond girl”. The process which begins with the medicine becoming science in the 19th century; a series of practices towards professional “nurses” and “women physicians”, exclusion of “midwives” who sustain traditional healing reinforced masculine characteristics of medicine and treatment. It is because, medical practices towards human body are regarded together with concepts such as rationalism, objectivity, classification, universality, generalization as a part of conceptual reality; these characteristics are identified with masculine characters, and the fact that human is a set of cohesion and values, therefore medicine is an occupation which also includes moral values should not be ignored. Evidence- based medicine paradigm which has been the issue in the recent years contributes scientific medicine become alienated from humaneness by taking clinic practices to background. In this study, it was aimed to discuss the evaluation of structural and masculine characteristics of scientific medicine, consideration of other problems caused by gendered structure of medicine and potentials that can be provided by female point of view in the actualization of humanistic medical practice. Keywords: Woman healing; Genderism; Science; History of medicine; Values of medicine. OZET Bir uygulamali bilim alani olarak tibbin tarihsel surecte erkek egemen bir bakis acisina, isleyis yapisina ve soyleme sahip oldugu; bu eril niteligin insan acisini dindirmeye yonelik buyusel pratiklerden geleneksel halk hekimligi uygulamalarina, tapinak tibbindan bilimsel-deneysel yonteme dayali klinik uygulamalara kadar genis bir yelpazede yasama gecirildigi gozlenmektedir. Tarihsel surec antik kulturlerin hastaliklari sagaltici “bilge” kadinlarindan ve “hekim” kralicelerinden Ortacag’in “cadi” avlarina ve bastan cikarici “sari kizlara” donusturuldugunun tanigidir. Ondokuzuncu yuzyilda tibbin bilimsellesmesiyle baslayan surec ise, profesyonellesen “hemsireler” ve “kadin hekimler”e yonelik bir dizi uygulama, geleneksel sifaciligi surduren “ebeler”in dislanmasi tibbin ve tedavi etme isinin eril niteligini saglamlastirmistir. Cunku olgusal gercekligin bir parcasi olarak insan bedenine yonelik tibbi uygulamalar, bilimsel yontemin temel nitelikleri olan akilcilik, nesnellik, siniflandirma, evrensellik, genelleyicilik gibi kavramlar esliginde ele alinmakta; bu nitelikler eril karakterle ozdeslestirilmekte, insanin ayni zamanda bir anlam ve degerler butunu oldugu, dolayisiyla hekimligin moral degerleri de iceren bir meslek oldugu gercegi gozden irak tutulmaktadir. Son donemde gundeme getirilen kanita dayali tip paradigmasi, klinik deneyimi deyim yerindeyse ikincil plana alan yaklasimiyla bilimsel tibbin giderek insancilliktan uzaklasmasina katkida bulunmaya aday bir gorunum sergilemektedir. Bu calismada bilimsel tibbin yapisal ozellikleri ve eril karakterinin degerlendirilmesi, tibbin cinsiyetci yapisindan kaynaklanan deger sorunlarinin ele alinmasi ve insancil bir tip uygulamasinin yasama gecirilmesinde kadin bakis acisinin saglayabilecegi olanaklarin tartisilmasi amaclanmistir. Anahtar Kelimeler: Kadin sifacilik; Cinsiyetcilik; Bilim; Tip tarihi; Tibbin degerleri
TL;DR: The researchers now hope to repurpose the only approved rho kinase inhibitor, Eril fasudil, which is marketed by Asahi Kasei Pharma to treat aneurysm.
Abstract: An Indiana University team has published the first evidence that rho kinase inhibitors could help treat AML and other hematological malignancies. The researchers now hope to repurpose the only approved rho kinase inhibitor, Eril fasudil, which is marketed by Asahi Kasei Pharma to treat aneurysm.
TL;DR: Kelimeler et al. as discussed by the authors showed that the male construction of modern politics is formed by dichotomy of reason/body and that modern politics which is constructed by this dichotomy is a structure of male politic is a form of politics that is exclusive sexuality of woman, is a sexual politics.
Abstract: Ozet: Modern dusunceye ickin kartezyen bakis akil ve beden arasinda aklin bedeni ‘oteki’ kildigi dikotomik bir iliski kurmustur. Eril bir bakis acisi egemen olan modern dusuncede akil erkegi temsil eder; oteki beden de oteki kadini. Ancak bu iliski biciminde erkegi temsil eden akil duzeni, hakikati, gucu ve aktifligi ..vb. simgelerken; kadini temsil eden beden ise duygusalligi, irrasyonelligi, zayifligi ve pasifligi ..vb. simgeler. Modern eril egemen anlayisin erkek ve kadin imgelerini olusturan bu eril simgesel formlarinin modern politikanin eril olusumunu gerceklestirdigi gorulecektir. Modern eril politika, bu tur bir dikotomik iliskinin erkege bir ustun ve ayricalik saglayan eril simgesel formlariyla kendini insa edecektir. Oysa modern eril dusuncenin (eril)akli ile bedenin insasi uzerinden urettigi bu eril politik yapi oteki beden ile ozdes kilinan oteki kadina egemen olan ve bu eril simgesel formlariyla da kendini surekli ureten cinsiyetci bir politikadir. Anahtar Kelimeler: Akil, beden, modernlik, cinsiyetci politika, kadin From Dichotomy of Reason/Body to Haunt of Modern Male Politic: A Note on Sexual Politics from Construction of Body Abstract: The basic issue of this article is a dichotomic relation between reason and body. While reason is identified with sexuality of man in modern idea, body is associated with sexuality of woman. Because of point of view of modern idea is a understanding of man-dominated, it has placed reason to against body. According to modern idea, reason is represented with absolutism, definiteness, truth, order, power and active etc.; body is impersonated as emotional, irrational, disordered, ambivalence, undecided, passive and weak etc. But body and sexuality of woman have been conceptualized as ‘other’ by this dichotomy; sexuality of man and his reason is named as subject of ‘other’. The main aim of this paper is to show that male construction of modern politics is formed by dichotomy of reason/body. Modern Politics which is constructed by this dichotomy is a structure of male politic and in order that structure of this male politic is a form of politics that is exclusive sexuality of woman, is a sexual politics. Keywords: Reason, body, modernity, gender policies, woman