TL;DR: The lymph node involvement is another manifestation of dissemination in infection with a dermotropic leishmania, and it appears that in some cases, instead of the parasite, it may be the leishmanial antigen that disseminates and produces lymphadenitis.
Abstract: In a study of zoonotic cutaneous leishmaniasis (CL) due to leishmania major in an endemic focus in Saudi Arabia, lymph node enlargement was observed in 66 of 643 patients (10.26%). The epitrochlear lymph nodes were most commonly involved (68%), but cervical (11%), axillary (15%), and inguinal (18%) lymph nodes were also involved. In eight patients (12%), two lymph node areas were involved. The affected lymph nodes were typically solitary, firm, mobile, nontender, only moderately enlarged, and appeared to persist beyond the clinical healing of the associated skin lesions. The results of pathologic and immunopathologic studies carried out on eight lymph nodes obtained from this group of patients supported the leishmanial etiology. Although amastigotes were only demonstrated in two lymph nodes, the leishmanial antigen was found in all eight specimens. The lymph node involvement is another manifestation of dissemination in infection with a dermotropic leishmania. It appears that in some cases, instead of the parasite, it may be the leishmanial antigen that disseminates and produces lymphadenitis.
TL;DR: Routine epitrochlear node clearance at the time of either elective or therapeutic axillary dissection for upper extremity melanoma is not indicated, however, it is desirable to perform an axillary Dissection whenever surgery for metastatic disease in an epitroChlear node is performed.
Abstract: Background: The incidence of epitrochlear lymph node metastasis for patients with melanomas on the hand or forearm is disputed, and management guidelines for these nodes are unclear.
TL;DR: This brief clinical report describes the management of a patient in whom epitrochlear lymph node metastases were identified by means of sentinel lymph node mapping, the surgical anatomy of the epitrofacial lymph node basin, and the technique of epitroChlear lymphadenectomy.
TL;DR: Fine‐needle aspiration appears to be a useful method for the diagnosis of Kaposi's sarcoma in developing countries, reducing the necessity for surgical lymph node excision.
Abstract: Fine-needle aspiration (FNA) cytology was performed on 15 patients with peripheral lymphadenopathy and/or skin lesions referred to the Department of Pathology of the Hospital Central of Maputo, Maputo, Mozambique. Epitrochlear lymph nodes were the most frequently aspirated site. All aspirates allowed diagnoses of Kaposi's sarcoma (KS). Smears contained loosely cohesive clusters of bland spindle cells, with a radial arrangement and nuclear crush artifacts. These diagnostic clues have not been described in other spindle-cell intranodal lesions that should be considered in differential diagnoses. Taking into consideration the high prevalence of AIDS and limited resources for diagnosis in Africa, FNA cytology appears to be a useful method for the diagnosis of KS in developing countries, reducing the necessity for surgical lymph node excision.
TL;DR: A 49-year-old Thai farmer presented with a 4-year history of chronic persistent discharging ulcer at the nail bed of the left middle finger after experiencing a minor trauma to the hyponychium and histological examination confirmed the diagnosis of subungual squamous cell carcinoma with left epitrochlear and axillary lymph node metastasis.
Abstract: Subungual squamous cell carcinoma is a rare disease that has been frequently misdiagnosed as benignity due to lack of awareness among doctors. The author reports a typical case of subungual squamous cell carcinoma in a 49-year-old Thai farmer who presented with a 4-year history of chronic persistent discharging ulcer at the nail bed of the left middle finger after experiencing a minor trauma to the hyponychium. Initially, he was treated as benign infection but the condition did not improve. The nail bed was biopsied and subungual squamous cell carcinoma was finally diagnosed. One small left epitrochlear lymph node and one large left axillary lymph node were palpable. He underwent amputation of the neck of the middle phalanx of the left middle finger and biopsy of ipsilateral epitrochlear lymph node and dissection of the affected axillary tissue. The histological examination confirmed the diagnosis of subungual squamous cell carcinoma with left epitrochlear and axillary lymph node metastasis. Radiotherapy was planned.