About: Ectopic kidney is a research topic. Over the lifetime, 510 publications have been published within this topic receiving 3305 citations. The topic is also known as: ectopic kidney.
TL;DR: A full review of the literature and a report of two cases of Crossed Renal Ectopia with Fusion will be presented, characterized by the extensive fusion of the two kidneys resulting in a so-called irreguIar renal mass.
Abstract: C ROSSED renaI ectopia is an uncommon anomaIy of the urinary tract, occurring once in every 7,000 autopsies [I]. In order to deveIop the clinical and radiographic picture of this condition further, a full review of the literature and a report of two cases 41 be presented. Crossed renal ectopia is a congenital condition in which a ureter in the norma bladder position crosses the midline to an ectopic kidney Iying on the opposite side of the body. This anomaly may be divided into four types (Fig. I) : Crossed Renal Ectopia with Fusion. This type is the most common of the four. (Fig. IA.) Abeshouse [2] in 1947 reported four cases and coIIected forty-seven reported since Wilmer’s review [j] in 1938, bringing the tota number to 337. Twenty-six cases have been collected since 1947 in addition to thirteen cases published prior to that year [d-343 and not included in the review by Abeshouse. In the absence of definite knowledge of the presence of fusion, our two cases have aIso been placed in this group. This ectopic form is characterized by fusion of the ectopic and normally positioned kidney. The resuIting renaI mass varies in anatomic form depending on the portion of the kidneys involved in the fusion. Six different forms of this anomaIy have been described. In all these forms axial rotation of both kidneys is impeded with the pelves located anteriorly. (Table I.) The most common form is the unilateral ,fused kidney with the ectopic kidney injerior. (Fig. 2A.) Second in frequency is the S-shaped or sigmoid kidney. This varies from the aforementioned in the degree of axia1 rotation of the ectopic kidney in reIationship to the norma kidney. (Fig. 2B.) The third form is the lump kidney. This is reIativeIy uncommon and is characterized by the extensive fusion of the two kidneys resulting in a soIid, irreguIar renal mass. The kidney mass is usuaIIy Iocated just above, or at the IeveI of, the sacra1 promontory. (Fig. 2C.)
TL;DR: In Xenopus and zebrafish both Osr1 and Osr2 are necessary and sufficient for the development of the pronephros and it is shown that Drosophila Odd induces kidney tissue in Xenopus.
TL;DR: Alternative approaches to treating nephrolithiasis may yield better outcomes and additional studies are needed to compare the various treatments for disease of the pelvic kidney in order to decide which options have the most beneficial outcomes.
Abstract: The incidence of pelvic kidney has been approximated at between 1 in 2200 and 1 in 3000. The ectopic kidney is thought to be no more susceptible to disease than the normally positioned kidney, except for the development of calculi and hydronephrosis. Because of the greater risk of injuring aberrant vessels or overlying abdominal viscera and nerves, the pelvic kidney presents special treatment challenges. Alternative approaches to treating nephrolithiasis may yield better outcomes. The tortuous ureter often associated with a pelvic kidney hinders deflection of the flexible ureteroscope, potentially limiting access. Laparoscopy-guided intervention permits visual exposure of the kidney, enhancing safe puncture and tract placement integral to percutaneous nephrolithotomy. Laparoscopy-assisted anterior retrograde percutaneous nephroscopy involves percutaneous access using a Hunter-Hawkins retrograde nephrostomy needle with adjunctive laparoscopy to permit viewing and manipulation of overlying bowel. Ureteropelvic junction (UPJ) obstruction has been reported to occur in 22% to 37% of ectopic kidneys. Endoscopic incision presents difficulties beyond those of anatomically normal kidneys. The laparoscopic approach provides good surgical exposure, and operative times are comparable to those of laparoscopic pyeloplasty in anatomically normal kidneys. To date, only a handful of cases of malignancy in a pelvic kidney have been described. Like a nonfunctioning anatomically normal kidney, a nonfunctional pelvic kidney may require primary removal. There are a few reports of laparoscopic pelvic nephrectomy. Additional studies are needed to compare the various treatments for disease of the pelvic kidney in order to decide which options have the most beneficial outcomes.
TL;DR: With proper precautions and meticulous technique, PCNL is a safe and effective modality to treat calculi in pelvic ectopic kidney.
Abstract: Background: Percutaneous nephrolithotomy (PCNL), although an accepted treatment modality in anatomically normal kidneys, is still not universally performed for calculi in pelvic ectopic ki...