TL;DR: The classical concept of the Asteroideae tribes has been confirmed in general, but recent investigations suggest numerous corrections, and some genera (e.g.Liabum, Echinops, Tarchonanthus, Arnica) do not fit into the scheme.
Abstract: Compositae (Asteraceae) are remarkably homogenous in basic type of inflorescence, flower and fruit. TheCichorioideae are more closely related to the other groups than usually realized. The classical concept of theAsteroideae tribes has been confirmed in general, but recent investigations (using palynology, carpology, phytochemistry etc.) suggest numerous corrections, and some genera (e.g.Liabum, Echinops, Tarchonanthus, Arnica) do not fit into the scheme. The tribes ofAsteroideae may be divided into two groups characterized by several common characters and common tendencies. The oldest reliable fossils are known from the borderline Oligocene/Miocene. Looking for the nearest relatives,Campanulales (incl.Calyceraceae) and—because of interesting phytochemical agreements—Araliales have to be discussed.
TL;DR: The results support the traditional uses for these plants but indicate that the active principles in the chloroform extracts are probably more active and/or are contained in larger concentrations than the principles inThe polar extracts used in the traditional medicine of North‐African countries.
Abstract: Aqueous, ethanol and chloroform extracts from Corrigiliola telephiifolia, Echinops spinosus, Kundmannia sicula, Tamarindus indica and Zygophyllum gaetulum were evaluated for antiinflammatory properties in mice (ear oedema induced by arachidonic acid) and rats (subplantar oedema induced by carrageenan) after topical or i.p. administration, respectively. Our results showed that all the plants exhibit antiinflammatory activity, since at least one extract from each plant was active in one of the experimental models. Whereas all the extracts of Corrigiliola telephiifolia and Echinops spinosus were highly active on all the experimental models assayed (values of inflammation inhibition well above 50%), poorer activity profiles were recorded in Kundmannia sicula, Tamarindus indica and Zygophyllum gaetulum. These results support the traditional uses for these plants but indicate that the active principles in the chloroform extracts are probably more active and/or are contained in larger concentrations than the principles in the polar extracts used in the traditional medicine of North-African countries.
TL;DR: The studied plants are potential cytotoxic drugs that deserve more detailed exploration in the future, to develop novel anticancer drugs against sensitive and otherwise drug-resistant phenotypes.
TL;DR: Among the bioactive extracts, the dichloromethane extract of the radix of Echinops ritro (Asteraceae) was the most potent and bioassay-guided fractionation of this extract led to the isolation of eight thiophenes.
Abstract: Extracts from 30 plants of the Greek flora were evaluated for their antifungal activity using direct bioautography assays with three Colletotrichum species. Among the bioactive extracts, the dichloromethane extract of the radix of Echinops ritro (Asteraceae) was the most potent. Bioassay-guided fractionation of this extract led to the isolation of eight thiophenes. Antifungal activities of isolated compounds together with a previously isolated thiophene from Echinops transiliensis were first evaluated by bioautography and subsequently evaluated in greater detail using a broth microdilution assay against plant pathogens Colletotrichum acutatum, Colletotrichum fragariae, Colletotrichum gloeosporioides, Botrytis cinerea, Fusarium oxysporum, Phomopsis viticola, and Phomopsis obscurans. 5‘-(3-Buten-1-ynyl)-2,2‘-bithiophen (1), α-terthienyl (2), and 2-[pent-1,3-diynyl]-5-[4-hydroxybut-1-ynyl]thiophene (5) at 3 and 30 μM were active against all three Colletotrichum species, F. oxysporum, P. viticola, and P. obsc...
TL;DR: Genome size was assessed by flow cytometry in 33 species belonging to seven genera of the tribe Cardueae (Asteraceae), which can be grouped in three taxonomic complexes, and correlated well with some karyological traits.