Topic
DSP-4
About: DSP-4 is a research topic. Over the lifetime, 93 publications have been published within this topic receiving 3027 citations.
Papers published on a yearly basis
Papers
TL;DR: DSP-4 crosses the placental barrier because when it was given to pregnant rats at the end of gestation, long-term changes were found in brain NA levels in their offspring, similar to those produced by the neonatal administration of the compound.
233 citations
TL;DR: The results indicate that DSP4 may be a useful denervation tool for studying various aspects of noradrenergic neurotransmission of developing locus coeruleus neurons.
148 citations
TL;DR: The results indicate that an intact noradrenergic system may be crucial for the observed ability of exercise to enhance full-length and exon I hippocampal BDNF mRNA expression, and suggest that the promoter linked toExon I may provide a major regulatory point for BDNF RNA expression in the dentate gyrus.
121 citations
TL;DR: Presynaptic PFC alpha2-adrenoreceptor (AR) binding site density, as determined by 3H-RX821002, suggests that axons from surviving noradrenergic neurons in the LC are sprouting to the PFC of subjects with dementia, and changes in postsynaptic AR would suggest a reduced function of the P FC.
95 citations
TL;DR: Results support the hypothesis that central noradrenergic mechanisms facilitate nigrostriatal and mesolimbic dopamine transmission in vivo and selectively reduce regional levels of Noradrenaline in the brain.
94 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2018 | 2 |
| 2015 | 2 |
| 2014 | 1 |
| 2013 | 3 |
| 2012 | 1 |
| 2011 | 2 |