Diffuse ST segment depression

Abstract: Hypothermia is known to cause specific electrocardiographic (EKG) changes such as Osborne waves and bradycardia. We report diffuse ST segment depression, an atypical EKG change, in a patient with a core temperature of 29.4°C (85°F). This patient had no previous cardiovascular pathology, and his EKG changes resolved gradually with aggressive warming. We also discuss the pathophysiology and clinical significance of ST depression in the general population and the typical EKG changes in hypothermia patients.

Abstract: A 54 year old man was admitted to our hospital with recent onset anginal chest pain. His ECG at the time of admission (panel) showed pronounced diffuse ST segment depression in leads V2–V6, I, aVL, II and aVF. It also showed ST segment elevation measuring 2 …

Abstract: Background Diffuse ST-segment depression in the inferior + anterolateral leads with ST-segment elevation in lead aVR has been described as characteristic of diffuse circumferential subendocardial ischemia caused by acute subtotal occlusion of the left main coronary artery. Methods Here we describe two patients admitted for acute neurological disorders who developed transient diffuse ST-segment depression in the inferior + anterolateral leads with ST-segment elevation in lead aVR, associated with elevation of cardiac troponin-I. Results In both cases subsequent coronary angiography did not show significant left main stenosis or “left main equivalent” narrowings. Conclusions As both patients had acute neurological disorders, a possible association between the two conditions is discussed.