TL;DR: In this paper, a mixture of devils claw and comfrey, preferably also including dandelion, burdock and nettles, is added to the animal's feed to alleviate the symptoms of osteoarthritis.
Abstract: A herbal based formulation for treatment of horses and dogs to alleviate the symptoms of osteoarthritis comprises a mixture of devils claw and comfrey, preferably also including dandelion, burdock and nettles, as an intimate admixture, added to the animal's feed.
TL;DR: In this article, a composition delivering effective amounts of Glucosamine, Devils Claw, SAM, and NSAID in a single dosage unit is presented, which can be used for emergency care.
Abstract: The present invention is a composition delivering effective amounts of Glucosamine, Devils Claw, SAM, and NSAID in a single dosage unit.
TL;DR: The lack of toxicity of these extracts and their growth inhibitory bioactivity against the bacterial triggers of several autoimmune inflammatory diseases indicates their potential for the prevention and treatment of rheumatoid arthritis, ankylosing spondylitis, multiple sclerosis and rheumatic fever.
TL;DR: Hp had no effect on the COX or 5-LOX arms of the AA cascade, as determined by whole blood aggregation and EIAs for PGE2 and LTB4, which would indicate that Hp does not share the same mechanism of action as standard nonsteroidal anti-inflammatory drugs and suggests that another mechanism is responsible for the anti- inflammatory and analgesic effects of Hp.
Abstract: The study was carried out to elucidate the mechanism(s) of action of the anti-inflammatory and analgesic properties of Harpagophytum procumbens (Hp; Devil's Claw) The in vitro effects of two preparations of Hp on the arachidonic acid cascade were monitored using whole blood aggregation
and enzyme immunoassays for prostaglandin E2 (PGE2) and leukotriene B4(LTB4), indices of cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) Neither Hp preparation significantly altered plasma
levels of PGE2 or serum levels of LTB4 Both preparations of Hp had no effect on the COX or 5-LOX arms of the AA cascade, as determined by whole blood aggregation and EIAs for PGE2 and LTB4 This would indicate that Hp does not share the same mechanism of action as standard nonsteroidal
anti-inflammatory drugs and suggests that another mechanism
is responsible for the anti-inflammatory and analgesic effects of Hp that have been observed in numerous animal and human clinical trials