TL;DR: The analysis of mouse mutants with impaired septation will provide valuable information on cellular mechanisms involved in valvuloseptal morphogenesis (a process often disrupted in congenital heart disease), while the study of embryonic lethal mouse mutants that present with lack of compaction of ventricular trabeculae will ultimately provide clues on the etiology of this abnormality in humans.
Abstract: Because of the increasing availability of tools for genetic manipulation, the mouse has become the most popular animal model for studying normal and abnormal cardiac development. However, despite t...
TL;DR: The conclusion was that os odontoideum was associated with an unrecognized fracture in children below the age of 5 with a previously normal odontoid structure as observed in this series.
Abstract: Introduction
Congenital and developmental osseous abnormalities and anomalies that affect the craniocervical junction complex can result in neural compression and vascular compromise and can manifest itself with abnormal cerebrospinal fluid dynamics. An understanding of the development of the craniocervical junction is essential to recognize the pathological abnormalities.
TL;DR: Gilbert as mentioned in this paper brings together 13 prominent embryologists and historians to write an account of that history and to explore the concepts that underlie not only modern embryology but also developmental and evolutionary biology.
Abstract: Although embryology is one of biology's principal disciplines, its history is often largely neglected. In this volume, Scott Gilbert brings together 13 prominent embryologists and historians to write an account of that history and to explore the concepts that underlie not only modern embryology but also developmental and evolutionary biology. The historical periods covered in the text range from the rebirth of comparative developmental anatomy in the 1800s to the synthesis with genetics in the 1960s. Topics include tissue interactions, relationships between genes and phenotype, the effects of cell surface in mediating organogenesis, and the nature of morphogenetic determinants. The concept of induction - from Pander and von Baer to Ephrussi and Waddington - is the book's predominant theme.